SRP72 and SRP68

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (biochemical)
HPRD (in vitro)

		SRP72	SRP68
Gene Name		signal recognition particle 72kDa	signal recognition particle 68kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Plasma Membrane	Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Ribosome Focal Adhesion
	Molecular Function	Signal Recognition Particle Binding 7S RNA Binding Poly(A) RNA Binding	Signal Recognition Particle Binding Signal Sequence Binding 7S RNA Binding Endoplasmic Reticulum Signal Peptide Binding Poly(A) RNA Binding
	Biological Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process Protein Targeting To ER
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane	Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)
Protein-Protein Interactions		5 interactors: CASP3 CASP6 FCHSD2 SKIL SRP68	1 interactors: SRP72
Entrez ID		6731	6730
HPRD ID		03671	05331
Ensembl ID			ENSG00000167881
Uniprot IDs		O76094	Q9UHB9
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epithelial Cell Differentiation Lymphocyte Homeostasis Execution Phase Of Apoptosis Leukocyte Homeostasis Epithelium Development Homeostasis Of Number Of Cells Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Tissue Development Protein Heterotrimerization Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Negative Regulation Of Cell Cycle Negative Regulation Of B Cell Proliferation Protein Homotrimerization Apoptotic DNA Fragmentation Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Platelet Formation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Programmed Cell Death Response To Growth Factor Platelet Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Cell Death Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Response To Cytokine Apoptotic Nuclear Changes Release Of Cytochrome C From Mitochondria Lens Fiber Cell Differentiation Protein Trimerization Regulation Of Activated T Cell Proliferation B Cell Homeostasis T Cell Homeostasis Negative Regulation Of B Cell Activation	SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Protein Localization To Endoplasmic Reticulum
Tagcloud ?		aa alongside aplastic associate autosomal causative coimmunoprecipitation dominant elucidating epitope excreted exome haplotype heterozygous idiopathic incorrectly inheritance inherited localize myelodysplasia nascent particle pathophysiology screen simplex snp tagged telomerase
Tagcloud (Difference) ?		aa alongside aplastic associate autosomal causative coimmunoprecipitation dominant elucidating epitope excreted exome haplotype heterozygous idiopathic incorrectly inheritance inherited localize myelodysplasia nascent particle pathophysiology screen simplex snp tagged telomerase
Tagcloud (Intersection) ?