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SULT2B1 and SULT1A1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SULT2B1
SULT1A1
Gene Name
sulfotransferase family, cytosolic, 2B, member 1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Endoplasmic Reticulum
Cytosol
Intracellular Membrane-bounded Organelle
Extracellular Vesicular Exosome
Cytosol
Molecular Function
Alcohol Sulfotransferase Activity
Protein Binding
Steroid Sulfotransferase Activity
Aryl Sulfotransferase Activity
Sulfotransferase Activity
Flavonol 3-sulfotransferase Activity
Steroid Sulfotransferase Activity
Biological Process
Sulfate Assimilation
Xenobiotic Metabolic Process
Steroid Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Catecholamine Metabolic Process
Xenobiotic Metabolic Process
Estrogen Metabolic Process
Amine Metabolic Process
Flavonoid Metabolic Process
Small Molecule Metabolic Process
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Phase II conjugation
Defective UGT1A1 causes hyperbilirubinemia
Cytosolic sulfonation of small molecules
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Dehydroepiandrosterone
Adenosine-3\'-5\'-Diphosphate
Pregnenolone
N-Cyclohexyltaurine
Adenosine-3\'-5\'-Diphosphate
P-Nitrophenol
Diseases
GWAS
Inflammatory bowel disease (
23128233
)
Inflammatory bowel disease (early onset) (
19915574
)
Protein-Protein Interactions
6 interactors:
ACYP2
ALS2CR12
PRICKLE3
SULT1A1
SULT1B1
SULT1E1
1 interactors:
SULT2B1
Entrez ID
6820
6817
HPRD ID
04991
01372
Ensembl ID
ENSG00000088002
ENSG00000196502
Uniprot IDs
O00204
P50225
PDB IDs
1Q1Q
1Q1Z
1Q20
1Q22
1LS6
1Z28
2D06
3QVU
3QVV
3U3J
3U3K
3U3M
3U3O
3U3R
4GRA
Enriched GO Terms of Interacting Partners
?
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Sulfation
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Xenobiotic Stimulus
Hormone Metabolic Process
Flavonoid Metabolic Process
Estrogen Metabolic Process
Purine Nucleoside Metabolic Process
Steroid Metabolic Process
Regulation Of Hormone Levels
Ribonucleotide Metabolic Process
Nucleoside Metabolic Process
Purine Nucleotide Metabolic Process
Ribose Phosphate Metabolic Process
Sulfur Compound Metabolic Process
Phenol-containing Compound Metabolic Process
Nucleotide Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Amine Metabolic Process
Organophosphate Metabolic Process
Organic Acid Metabolic Process
Phosphate-containing Compound Metabolic Process
Lipid Metabolic Process
Thyroid Hormone Metabolic Process
Catecholamine Metabolic Process
Small Molecule Metabolic Process
Cellular Biogenic Amine Metabolic Process
Sulfate Assimilation
3'-phosphoadenosine 5'-phosphosulfate Metabolic Process
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Response To Xenobiotic Stimulus
Purine Nucleoside Metabolic Process
Steroid Metabolic Process
Ribonucleotide Metabolic Process
Nucleoside Metabolic Process
Purine Nucleotide Metabolic Process
Ribose Phosphate Metabolic Process
Sulfur Compound Metabolic Process
Nucleotide Metabolic Process
Tagcloud
?
1a
akr1c3
androgenic
androstenedione
comt
cyp19a1
cyp1b1
cyp3a5
e1s
ers
esr2
estrogens
extents
gper
gstp1
hec
hieec
hsd17b1
hsd17b12
hsd17b7
hsd3b2
hydroxyestrogens
ishikawa
metabolized
nqo2
quinones
sulfatase
ugt2b7
Tagcloud (Difference)
?
1a
akr1c3
androgenic
androstenedione
comt
cyp19a1
cyp1b1
cyp3a5
e1s
ers
esr2
estrogens
extents
gper
gstp1
hec
hieec
hsd17b1
hsd17b12
hsd17b7
hsd3b2
hydroxyestrogens
ishikawa
metabolized
nqo2
quinones
sulfatase
ugt2b7
Tagcloud (Intersection)
?