SULT2B1 and SULT1E1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		SULT2B1	SULT1E1
Gene Name		sulfotransferase family, cytosolic, 2B, member 1	sulfotransferase family 1E, estrogen-preferring, member 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Cytosol
	Molecular Function	Alcohol Sulfotransferase Activity Protein Binding Steroid Sulfotransferase Activity	Estrone Sulfotransferase Activity Steroid Binding Flavonol 3-sulfotransferase Activity Steroid Sulfotransferase Activity
	Biological Process	Sulfate Assimilation Xenobiotic Metabolic Process Steroid Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process	Xenobiotic Metabolic Process Female Pregnancy Steroid Metabolic Process Estrogen Metabolic Process Small Molecule Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways			Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective UGT1A4 causes hyperbilirubinemia Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Cytosolic sulfonation of small molecules Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GGT1 causes Glutathionuria (GLUTH) Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs		Dehydroepiandrosterone Adenosine-3\'-5\'-Diphosphate Pregnenolone N-Cyclohexyltaurine	Cyclizine Adenosine-3\'-5\'-Diphosphate 3\'-Phosphate-Adenosine-5\'-Phosphate Sulfate 3,5,3\',5\'-Tetrachloro-Biphenyl-4,4\'-Diol
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ACYP2 ALS2CR12 PRICKLE3 SULT1A1 SULT1B1 SULT1E1	13 interactors: BMPR2 C14orf1 COPS6 EEF1A1 ENOX1 IGSF21 LRIF1 PDE9A RBM48 SETDB1 SULT2B1 TP53 UNC119
Entrez ID		6820	6783
HPRD ID		04991	08966
Ensembl ID		ENSG00000088002	ENSG00000109193
Uniprot IDs		O00204	P49888 Q53X91
PDB IDs		1Q1Q 1Q1Z 1Q20 1Q22	1G3M 1HY3 4JVL 4JVM 4JVN
Enriched GO Terms of Interacting Partners?		3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Response To Xenobiotic Stimulus Hormone Metabolic Process Flavonoid Metabolic Process Estrogen Metabolic Process Purine Nucleoside Metabolic Process Steroid Metabolic Process Regulation Of Hormone Levels Ribonucleotide Metabolic Process Nucleoside Metabolic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Sulfur Compound Metabolic Process Phenol-containing Compound Metabolic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Amine Metabolic Process Organophosphate Metabolic Process Organic Acid Metabolic Process Phosphate-containing Compound Metabolic Process Lipid Metabolic Process Thyroid Hormone Metabolic Process Catecholamine Metabolic Process Small Molecule Metabolic Process Cellular Biogenic Amine Metabolic Process
Tagcloud ?		1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 estrogens extents gper gstp1 hec hieec hsd17b1 hsd17b12 hsd17b7 hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones sulfatase ugt2b7	analyzing bovine caruncular catalyzed conflict conflicting esr esrs estrogens expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually
Tagcloud (Difference) ?		1a akr1c3 androgenic androstenedione comt cyp19a1 cyp1b1 cyp3a5 e1s ers esr2 extents gper gstp1 hec hieec hsd17b1 hsd17b12 hsd17b7 hsd3b2 hydroxyestrogens ishikawa metabolized nqo2 quinones ugt2b7	analyzing bovine caruncular catalyzed conflict conflicting esr esrs expresses giant placentas pools posttranscriptional produces resolve sorting sulfonation tgc tgcs transcript trophoblast unable uninucleated utc utcs virtually
Tagcloud (Intersection) ?		estrogens sulfatase