ACP1 and EPHB1

Number of citations of the paper that reports this interaction (PMID 9499402)
66

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		ACP1	EPHB1
Gene Name		acid phosphatase 1, soluble	EPH receptor B1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Early Endosome Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Acid Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity
	Biological Process	Peptidyl-tyrosine Dephosphorylation	Angiogenesis Axon Guidance Peptidyl-tyrosine Phosphorylation Optic Nerve Morphogenesis Central Nervous System Projection Neuron Axonogenesis Neurogenesis Establishment Of Cell Polarity Retinal Ganglion Cell Axon Guidance Cell-substrate Adhesion Regulation Of JNK Cascade Protein Autophosphorylation Ephrin Receptor Signaling Pathway Camera-type Eye Morphogenesis Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Positive Regulation Of Synapse Assembly Cell Chemotaxis Dendritic Spine Development Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Regulation Of Neuron Death
Pathways			EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		15 interactors: BARD1 CTNNB1 EPHA2 EPHB1 EPHB2 FABP4 FNBP1L FYN INSR KDR LCK MRPL20 SFMBT1 SPTAN1 ZAP70	11 interactors: ACP1 EFNA1 EFNA5 EFNB1 EFNB2 EPHB6 GRB10 GRB2 NCK1 PRKCG PXN
Entrez ID		52	2047
HPRD ID		08881	02790
Ensembl ID		ENSG00000143727	ENSG00000154928
Uniprot IDs		B5MCC7 P24666 Q59EH3	P54762
PDB IDs		1XWW 3N8I 5PNT	2DJS 2EAO
Enriched GO Terms of Interacting Partners?		Peptidyl-tyrosine Phosphorylation Peptidyl-tyrosine Autophosphorylation Protein Autophosphorylation Movement Of Cell Or Subcellular Component Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Locomotion Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Ephrin Receptor Signaling Pathway Cell Migration Developmental Process Regulation Of Phosphorylation Protein Phosphorylation Cell Differentiation Regulation Of Cellular Component Organization Cell Motility Camera-type Eye Morphogenesis Regulation Of Phosphorus Metabolic Process Response To Growth Factor Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Adhesion Angiogenesis Cell Morphogenesis Eye Morphogenesis Cell Morphogenesis Involved In Differentiation Axon Guidance Anatomical Structure Morphogenesis Regulation Of Intracellular Signal Transduction Blood Vessel Morphogenesis Phosphorylation Positive Regulation Of Intracellular Signal Transduction Optic Nerve Morphogenesis Cell Projection Morphogenesis Positive Regulation Of Cell Differentiation Cell Part Morphogenesis Cardiovascular System Development Dendrite Morphogenesis Blood Vessel Development Axonogenesis Vasculature Development Dendritic Spine Morphogenesis Viral Process Anatomical Structure Development Organ Development Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation T Cell Aggregation T Cell Activation Optic Nerve Development	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axon Guidance Cell Morphogenesis Involved In Differentiation Ephrin Receptor Signaling Pathway Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Neuron Projection Development Cell Surface Receptor Signaling Pathway Cell Projection Morphogenesis Cell Part Morphogenesis Movement Of Cell Or Subcellular Component Neuron Development Neuron Differentiation Cell Development Locomotion Nervous System Development Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Signal Transduction Response To External Stimulus Regulation Of Cell Adhesion Signaling Cell Communication Regulation Of Phosphorylation Regulation Of Cell-cell Adhesion Signal Complex Assembly Multicellular Organismal Development Cell Differentiation Regulation Of Phosphorus Metabolic Process Cell Migration Cellular Response To Stimulus Anatomical Structure Development Cell Motility Cell-cell Signaling Positive Regulation Of Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Developmental Process System Development Positive Regulation Of T Cell Activation Cell Adhesion Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Signal Transduction
Tagcloud ?		ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written	anlage b3 cascades cortical cue endogenously entering ephrin fak gives interneurons migrate migrating misrouted path pfak poa preoptic psrc repulsion repulsive reverse stop str striatal striatum superficial terminate
Tagcloud (Difference) ?		ada ada2 additive adenosine allele approved cad carriers codon committee consent contribution deaminase diabetic donors ethical functionally give hints informed multifactorial note phosphatse proportion ptpn22 simultaneous strength stresses written	anlage b3 cascades cortical cue endogenously entering ephrin fak gives interneurons migrate migrating misrouted path pfak poa preoptic psrc repulsion repulsive reverse stop str striatal striatum superficial terminate
Tagcloud (Intersection) ?