SIGLEC1

Gene Name		sialic acid binding Ig-like lectin 1, sialoadhesin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Membrane
	Molecular Function	Carbohydrate Binding
	Biological Process	Endocytosis Inflammatory Response Cell-matrix Adhesion Single Organismal Cell-cell Adhesion Positive Regulation Of T Cell Apoptotic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: MUC1 SPN TNR
Entrez ID		6614
HPRD ID		02854
Ensembl ID		ENSG00000088827
Uniprot IDs		Q9BZZ2
PDB IDs
Enriched GO Terms of Interacting Partners?		Associative Learning Negative Regulation Of Cell-cell Adhesion Learning Negative Regulation Of Axon Extension Involved In Regeneration Negative Regulation Of Cell Adhesion Negative Regulation Of Type IV Hypersensitivity Learning Or Memory Cognition Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Cell-cell Adhesion Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Axon Regeneration Positive Regulation Of Transmission Of Nerve Impulse Single-organism Behavior Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Transmission Of Nerve Impulse Locomotory Exploration Behavior Single Organismal Cell-cell Adhesion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Negative Thymic T Cell Selection Negative Regulation Of Acute Inflammatory Response Negative Regulation Of T Cell Mediated Immunity Negative T Cell Selection Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Behavior Chemotaxis Neuron Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of Histone H4 Acetylation Regulation Of Mammary Gland Epithelial Cell Proliferation Regulation Of Axon Regeneration Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Histone Acetylation Thymic T Cell Selection Positive Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Axon Extension Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein Acetylation Response To Protozoan Exploration Behavior Cell Migration Cell Motility
Tagcloud ?		alternative biomarker ccr1 cd14 cluster clustering clusters complication cutaneous diffuse distinguished exclusively greatly hierarchical idiopathic ifn il13ra1 immunoassay lcssc messenger monocyte mononuclear mrc1 mx1 pah pbmc pbmcs ssc supervised