STEAP3

Gene Name		STEAP family member 3, metalloreductase
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Gene Ontology Annotations	Cellular Component	Multivesicular Body Plasma Membrane Endosome Membrane Integral Component Of Membrane
	Molecular Function	Ferric-chelate Reductase Activity Protein Binding Cupric Reductase Activity Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity
	Biological Process	Cellular Iron Ion Homeostasis Apoptotic Process Cell Cycle Protein Secretion Copper Ion Import Transferrin Transport Transmembrane Transport Oxidation-reduction Process Ferric Iron Import Into Cell Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Exosomal Secretion
Pathways		Iron uptake and transport Transferrin endocytosis and recycling
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: BAD BNIP3L PKMYT1 SETD7 TPT1
Entrez ID		55240
HPRD ID		10285
Ensembl ID		ENSG00000115107
Uniprot IDs		B8ZZX6 Q658P3
PDB IDs		2VNS 2VQ3
Enriched GO Terms of Interacting Partners?		Response To Virus Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Mitochondrial Membrane Organization Apoptotic Mitochondrial Changes Cellular Response To Chromate Response To Other Organism Response To Biotic Stimulus Positive Regulation Of Mitochondrial Membrane Potential Suppression By Virus Of Host Apoptotic Process Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Mitochondrial Protein Catabolic Process Negative Regulation Of Cell Death Positive Regulation Of Apoptotic Process By Virus Glucose Catabolic Process Positive Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Glucokinase Activity Peptidyl-lysine Monomethylation Response To Chromate Organelle Organization Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Cellular Process Regulating Host Cell Cycle In Response To Virus Cellular Response To Nicotine Apoptotic Signaling Pathway Mitochondrial Outer Membrane Permeabilization Regulation Of Apoptotic Process Response To Oleic Acid Pore Complex Assembly Modulation By Virus Of Host Process Peptidyl-lysine Dimethylation Type B Pancreatic Cell Proliferation Regulation Of Cell Death ADP Metabolic Process Mitochondrion Organization Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Virus Positive Regulation Of B Cell Differentiation Heterochromatin Organization Response To External Stimulus Positive Regulation Of Mitochondrial Membrane Permeability Modulation By Virus Of Host Morphology Or Physiology Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Killing Of Cells Of Other Organism
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