KLHL23 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		KLHL23	ANXA7
Gene Name		kelch-like family member 23	annexin A7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process		Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: ANXA1 ANXA7 BNIP3L CDKN1A TK1	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		151230	310
HPRD ID		11320	01720
Ensembl ID		ENSG00000213160	ENSG00000138279
Uniprot IDs		Q8NBE8	B2R657 P20073
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Glucocorticoid Response To Corticosteroid Response To Organic Cyclic Compound Response To X-ray Response To Inorganic Substance Response To Steroid Hormone Epithelial Cell Differentiation Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Neutrophil Clearance Fetal Process Involved In Parturition Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Digestive Tract Development Response To Ionizing Radiation Digestive System Development DNA Rewinding Positive Regulation Of Neutrophil Apoptotic Process Skeletal Muscle Cell Proliferation Liver Development Response To Lipid Negative Regulation Of Apoptotic Process Response To Toxic Substance Negative Regulation Of Programmed Cell Death Response To Organic Substance Negative Regulation Of Phospholipase A2 Activity Mitochondrial Protein Catabolic Process Response To Hormone Negative Regulation Of Cell Death Negative Regulation Of Interleukin-8 Secretion Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Epithelium Development Response To Abiotic Stimulus Regulation Of Cell Cycle Phase Transition Intestinal Epithelial Cell Maturation Prolactin Secretion Response To Cortisol Positive Regulation Of Prostaglandin Biosynthetic Process Thymidine Metabolic Process Negative Regulation Of Phospholipase Activity Positive Regulation Of Cell Cycle Cellular Response To UV-B Deoxyribonucleoside Monophosphate Biosynthetic Process Defense Response Response To Metal Ion Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Response To Stress Apoptotic Signaling Pathway	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?			annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?