SNRPE and SMN2

Number of citations of the paper that reports this interaction (PMID 9323129)
127

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SNRPE	SMN2
Gene Name		small nuclear ribonucleoprotein polypeptide E	survival of motor neuron 2, centromeric
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Vesicular Exosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Cajal Body Z Disc SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process Hair Cycle	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly Nervous System Development Gene Expression NcRNA Metabolic Process
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination	snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: CLNS1A DDX20 GEMIN5 GEMIN6 GEMIN7 HRAS IL7R LSM2 LSM3 LSM4 LSM5 SMN1 SMN2 SNRPD3 SNRPF SNRPG STRAP WDR77 YWHAQ	24 interactors: BLOC1S6 BYSL CHTOP DDX20 DHX9 FAM9B FBL GAR1 GEMIN2 HNRNPUL1 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG TIAL1 VPS28
Entrez ID		6635	6607
HPRD ID		00548	09036
Ensembl ID			ENSG00000205571
Uniprot IDs		P62304	B4DP61 Q16637
PDB IDs		1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77	1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly NcRNA Metabolic Process RNA Metabolic Process Gene Expression Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Spliceosomal Complex Assembly Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process DNA-templated Transcription, Termination Cellular Metabolic Process MRNA 3'-end Processing RNA 3'-end Processing Aromatic Compound Catabolic Process Regulation Of Epithelial Cell Proliferation Interleukin-7-mediated Signaling Pathway Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Process Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of T Cell Mediated Cytotoxicity Cellular Macromolecule Catabolic Process Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Ruffle Assembly	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly RNA Splicing RNA Processing MRNA Processing Ribonucleoprotein Complex Biogenesis NcRNA Metabolic Process MRNA Metabolic Process Ribonucleoprotein Complex Assembly RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Histone MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Spliceosomal Complex Assembly Cellular Nitrogen Compound Metabolic Process DNA-templated Transcription, Termination Cellular Macromolecular Complex Assembly Nitrogen Compound Metabolic Process Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing RNA 3'-end Processing Cellular Metabolic Process Cellular Component Assembly Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RRNA Processing RRNA Metabolic Process Metabolic Process Ribosome Biogenesis Histone Glutamine Methylation Cellular Process Transcription, RNA-templated Peptidyl-glutamine Methylation Positive Regulation Of Type I Interferon Production Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway DNA-templated Transcription, Elongation SnoRNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process CRD-mediated MRNA Stabilization Regulation Of Type I Interferon Production Endosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Helicase Activity Secretion Of Lysosomal Enzymes Late Endosome To Vacuole Transport Osteoblast Differentiation
Tagcloud ?			atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Difference) ?			atrophy centromeric compensate copies copy degeneration deletions detectable display donor easily exon fails fatal harbor hindering homozygous infant intragenic italian modifier muscular null predictable sma smn1 splice unusually weakness
Tagcloud (Intersection) ?