SNRPE

Gene Name		small nuclear ribonucleoprotein polypeptide E
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome PICln-Sm Protein Complex SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex Extracellular Vesicular Exosome Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription Histone MRNA Metabolic Process RNA Splicing Gene Expression MRNA 3'-end Processing NcRNA Metabolic Process Hair Cycle
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Metabolism of non-coding RNA mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs snRNP Assembly Processing of Capped Intronless Pre-mRNA SLBP independent Processing of Histone Pre-mRNAs RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-protein Interactions		19 interactors: CLNS1A DDX20 GEMIN5 GEMIN6 GEMIN7 HRAS IL7R LSM2 LSM3 LSM4 LSM5 SMN1 SMN2 SNRPD3 SNRPF SNRPG STRAP WDR77 YWHAQ
Entrez ID		6635
HPRD ID		00548
Ensembl ID
Uniprot IDs		P62304
PDB IDs		1VU2 1VU3 2Y9A 2Y9B 2Y9C 2Y9D 3CW1 3PGW 3S6N 4F77
Enriched GO Terms of Interacting Partners?		Spliceosomal SnRNP Assembly RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Assembly Ribonucleoprotein Complex Biogenesis Cellular Macromolecular Complex Assembly NcRNA Metabolic Process RNA Metabolic Process Gene Expression Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Spliceosomal Complex Assembly Histone MRNA Metabolic Process Termination Of RNA Polymerase II Transcription Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process DNA-templated Transcription, Termination Cellular Metabolic Process MRNA 3'-end Processing RNA 3'-end Processing Aromatic Compound Catabolic Process Regulation Of Epithelial Cell Proliferation Interleukin-7-mediated Signaling Pathway Metabolic Process Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cellular Process Positive Regulation Of Rac Protein Signal Transduction Negative Regulation Of T Cell Mediated Cytotoxicity Cellular Macromolecule Catabolic Process Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Ruffle Assembly
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