ARK2N and JAKMIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARK2N	JAKMIP1
Description		arkadia (RNF111) N-terminal like PKA signaling regulator 2N	janus kinase and microtubule interacting protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Cytoplasm Cytoskeleton Microtubule Membrane Ribonucleoprotein Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Ubiquitin Protein Ligase Activity	RNA Binding Protein Binding Microtubule Binding Kinase Binding GABA Receptor Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Release From Viral Latency Negative Regulation Of DNA-templated Transcription Negative Regulation Of Viral Life Cycle	Protein Transport Cognition
Pathways
Drugs
Diseases
GWAS			Coronary artery disease in type 1 diabetes ( 29695241) Response to angiotensin II receptor blocker therapy ( 22566498) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Tau burden ( 33426524)
Interacting Genes		15 interacting genes: DDIT4L ERG JAKMIP1 LRRK2 MCRS1 MORC3 RNF4 SRPK1 SRPK2 SUMO1 SUMO1P1 SUMO2 TAX1BP1 UBC UBE2I	21 interacting genes: ARK2N BLK CBX8 CHRM3 DDX6 DSCR9 ENKD1 FXR1 GABBR1 IL16 JAK1 MCRS1 MRPL11 PSMB1 SCNM1 TSGA10IP TYK2 USP2 YES1 YWHAG ZNHIT2
Entrez ID		147339	152789
HPRD ID		12690	11292
Ensembl ID		ENSG00000152242	ENSG00000152969
Uniprot IDs		Q96B23	B3KWB6 Q96N16
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification Process PML Body Protein Tag Activity Protein Metabolic Process Presynaptic Cytosol Protein Sumoylation Nuclear Body Organization Transcription Factor Binding Protein Modification By Small Protein Conjugation Ubiquitin-like Protein Ligase Binding Postsynaptic Cytosol Post-translational Protein Modification Macromolecule Metabolic Process Small Protein Activating Enzyme Binding Protein Phosphorylation Phosphorylation RNA Binding PML Body Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleoplasm Nucleus Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process SUMO Transferase Activity Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Nuclear Body Positive Regulation Of Viral Genome Replication Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Magnesium Ion Binding Spliceosomal Complex Assembly Negative Regulation Of Viral Genome Replication Peptidyl-serine Phosphorylation SUMO Conjugating Enzyme Activity Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Glutamatergic Synapse Negative Regulation Of Intracellular Transport Positive Regulation Of Viral Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Protein Localization To Phagocytic Vesicle Negative Regulation Of Late Endosome To Lysosome Transport Amphisome	Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Growth Hormone Receptor Binding Interleukin-10-mediated Signaling Pathway Type III Interferon-mediated Signaling Pathway Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Type II Interferon-mediated Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT
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