NOVA1 and SMARCC2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		NOVA1	SMARCC2
Gene Name		neuro-oncological ventral antigen 1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Intracellular Membrane-bounded Organelle	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Transcriptional Repressor Complex Protein Complex NpBAF Complex NBAF Complex
	Molecular Function	RNA Binding MRNA Binding Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing Synaptic Transmission Locomotory Behavior RNA Splicing Regulation Of RNA Metabolic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Nucleosome Disassembly Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP PCBP1 RPP14 SMARCC2 SRPK1	21 interactors: ARRB2 ATXN1 ATXN1L BAZ1B C11orf74 CSNK2A1 GATA1 ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TERF1 TERF2IP
Entrez ID		4857	6601
HPRD ID		03693	03437
Ensembl ID		ENSG00000139910	ENSG00000139613
Uniprot IDs		B7Z770 P51513	F8VXC8 Q8TAQ2
PDB IDs		1DT4 2ANN 2ANR
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process MRNA Processing MRNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Synaptic Growth At Neuromuscular Junction Cellular Nitrogen Compound Metabolic Process Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Neuron Remodeling Sperm Chromatin Condensation Gene Expression RNA Splicing Nucleosome Disassembly Forebrain Development Forebrain Neuron Fate Commitment Cellular Copper Ion Homeostasis Positive Regulation Of Viral Genome Replication Regulation Of Transcription Involved In Cell Fate Commitment Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle	Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Cellular Process Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Chromosome Organization Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Developmental Process Nitrogen Compound Metabolic Process Regulation Of Signaling Myeloid Cell Differentiation Negative Regulation Of Chromosome Organization Regulation Of Organelle Organization Biosynthetic Process Regulation Of Cellular Component Organization Anatomical Structure Development Negative Regulation Of Binding Erythrocyte Differentiation System Development Rhythmic Process Response To Stimulus Erythrocyte Homeostasis Regulation Of Telomere Maintenance Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Gene Expression RNA-dependent DNA Replication Megakaryocyte Differentiation Myeloid Cell Homeostasis Organ Development
Tagcloud ?		181b 5p astrocytoma astrocytomas changing downregulated downregulating ectopic invasion inversely micrornas mir mirna mirnas modulate neuro neuroepithelial noncoding numerous oncogenes oncological overexpressed restoring reversed rnas suppressors untranslated utr ventral	affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2
Tagcloud (Difference) ?		181b 5p astrocytoma astrocytomas changing downregulated downregulating ectopic invasion inversely micrornas mir mirna mirnas modulate neuro neuroepithelial noncoding numerous oncogenes oncological overexpressed restoring reversed rnas suppressors untranslated utr ventral	affymetrix arrays c10orf18 cabp4 capn10 centb1 converted fdr fractioned genechip glycerol hybridized or4c6 papillary ran sall1 serous spata13 splicing st st18 subcellular supernatants supraspliceosome transcriptome wdr78 znf263 zp2 zranb2
Tagcloud (Intersection) ?