SLC9A1 and CHP2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		SLC9A1	CHP2
Description		solute carrier family 9 member A1	calcineurin like EF-hand protein 2
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Focal Adhesion Cell Surface Intercalated Disc Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium T-tubule Sarcolemma Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome Cation-transporting ATPase Complex Transporter Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Calmodulin Binding Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Protein Phosphatase 2B Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Calcium-dependent Protein Binding Molecular Adaptor Activity	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Intracellular Sodium Ion Homeostasis Regulation Of PH Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cell Migration Maintenance Of Cell Polarity Cell Differentiation Positive Regulation Of Cell Growth Cellular Response To Insulin Stimulus Positive Regulation Of Mitochondrial Membrane Permeability Response To Muscle Stretch Sodium Ion Export Across Plasma Membrane Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Action Potential Positive Regulation Of Transcription By RNA Polymerase II Stem Cell Differentiation Protein Complex Oligomerization Regulation Of Intracellular PH Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Cardiac Muscle Cell Differentiation Transmembrane Transport Cellular Response To Cold Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Antibiotic Cellular Response To Electrical Stimulus Cellular Response To Mechanical Stimulus Cellular Response To Hypoxia Cellular Response To Acidic PH Potassium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Cardiac Muscle Cell Contraction Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Sodium Ion Import Across Plasma Membrane Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Intracellular Signal Transduction Proton Transmembrane Transport	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion
Pathways		Hyaluronan degradation Sodium/Proton exchangers
Drugs		Amiloride Homoserine Lactone Cariporide
Diseases
GWAS		Lateral ventricle volume ( 31530798)	Daytime nap ( 33568662)
Interacting Genes		12 interacting genes: CA2 CHP1 CHP2 DAXX MAP3K14 MAP4K4 MAPK1 MAPK14 MDFI TESC WNK1 YWHAB	6 interacting genes: MDFI SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5
Entrez ID		6548	63928
HPRD ID		00123	14259
Ensembl ID		ENSG00000090020	ENSG00000166869
Uniprot IDs		B2RAH2 P19634	O43745
PDB IDs		1Y4E 2BEC 2E30 2HTG 2KBV 2L0E 2MDF 2YGG 6BJF 6NUC 6NUF 6NUU 6ZBI 7DSV 7DSW 7DSX	2BEC
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity MAPK Cascade Positive Regulation Of Sodium:proton Antiporter Activity Protein Kinase Activity Regulation Of Cellular Localization Intracellular Signaling Cassette Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Calcineurin-mediated Signaling Regulation Of Sodium Ion Transmembrane Transport Regulation Of Intracellular Protein Transport Protein Kinase Inhibitor Activity Kinase Activity Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Transport Regulation Of Phosphatase Activity Regulation Of Sodium Ion Transport Negative Regulation Of Protein Localization Positive Regulation Of Keratinocyte Migration Intracellular Signal Transduction Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular PH Positive Regulation Of Myotube Differentiation Regulation Of Protein Localization Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Calcium-mediated Signaling Regulation Of PH Positive Regulation Of Cell Migration MAP Kinase Activity Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Biosynthetic Process Negative Regulation Of Protein Import Into Nucleus Regulation Of RNA Metabolic Process Positive Regulation Of Locomotion Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Phosphate Metabolic Process Pyrimidine Nucleobase Metabolic Process Negative Regulation Of Calcium-mediated Signaling Stress-activated MAPK Cascade	Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Sodium Ion Import Across Plasma Membrane Regulation Of Cellular PH Regulation Of Intracellular PH Antiporter Activity Inorganic Cation Import Across Plasma Membrane Regulation Of PH Sodium Ion Transmembrane Transport Import Across Plasma Membrane Potassium Ion Transmembrane Transport Proton Transmembrane Transport Potassium Ion Transport Sodium Ion Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Cellular Homeostasis Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Chemical Homeostasis Apical Plasma Membrane Monoatomic Ion Transport Transmembrane Transport Homeostatic Process Recycling Endosome Membrane Regulation Of The Force Of Heart Contraction By Cardiac Conduction Cation-transporting ATPase Complex Regulation Of Biological Quality Transporter Complex Transepithelial Ammonium Transport Positive Regulation Of The Force Of Heart Contraction Glandular Epithelial Cell Development Regulation Of Cardiac Muscle Cell Membrane Potential Protein Phosphatase 2B Binding Neuron Spine Dynactin Complex Gastric Acid Secretion Cardiac Muscle Cell Contraction Positive Regulation Of Action Potential Arrestin Family Protein Binding Cellular Response To Antibiotic Basolateral Plasma Membrane
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?