CHP2 and SLC9A4

Number of citations of the paper that reports this interaction (PubMedID 12576672)
0

Data Source:
BioGRID (pull down)

		CHP2	SLC9A4
Description		calcineurin like EF-hand protein 2	solute carrier family 9 member A4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Membrane	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Zymogen Granule Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion	Gastric Acid Secretion Glandular Epithelial Cell Development Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Regulation Of PH Regulation Of Intracellular PH Transmembrane Transport Transepithelial Ammonium Transport Potassium Ion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport
Pathways			Sodium/Proton exchangers
Drugs
Diseases
GWAS		Daytime nap ( 33568662)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Appendicular lean mass ( 33097823) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Celiac disease ( 25920553 30572963 18311140) Crohn's disease ( 28067908) Delirium ( 29631748) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Night sleep phenotypes ( 27126917) Serum protein levels (sST2) ( 23999434) White blood cell types ( 21738478)
Interacting Genes		6 interacting genes: MDFI SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5	2 interacting genes: CHP1 CHP2
Entrez ID		63928	389015
HPRD ID		14259	15973
Ensembl ID		ENSG00000166869	ENSG00000180251
Uniprot IDs		O43745	Q6AI14
PDB IDs		2BEC
Enriched GO Terms of Interacting Partners?		Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Sodium Ion Import Across Plasma Membrane Regulation Of Cellular PH Regulation Of Intracellular PH Antiporter Activity Inorganic Cation Import Across Plasma Membrane Regulation Of PH Sodium Ion Transmembrane Transport Import Across Plasma Membrane Potassium Ion Transmembrane Transport Proton Transmembrane Transport Potassium Ion Transport Sodium Ion Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Cellular Homeostasis Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Chemical Homeostasis Apical Plasma Membrane Monoatomic Ion Transport Transmembrane Transport Homeostatic Process Recycling Endosome Membrane Regulation Of The Force Of Heart Contraction By Cardiac Conduction Cation-transporting ATPase Complex Regulation Of Biological Quality Transporter Complex Transepithelial Ammonium Transport Positive Regulation Of The Force Of Heart Contraction Glandular Epithelial Cell Development Regulation Of Cardiac Muscle Cell Membrane Potential Protein Phosphatase 2B Binding Neuron Spine Dynactin Complex Gastric Acid Secretion Cardiac Muscle Cell Contraction Positive Regulation Of Action Potential Arrestin Family Protein Binding Cellular Response To Antibiotic Basolateral Plasma Membrane	Regulation Of Phosphatase Activity Regulation Of Dephosphorylation Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Protein Import Into Nucleus Regulation Of Calcium-mediated Signaling Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Protein Transport Regulation Of Protein Localization To Nucleus Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Negative Regulation Of Phosphatase Activity Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Protein Glycosylation Transporter Complex Positive Regulation Of Phosphatase Activity Positive Regulation Of Protein Localization Negative Regulation Of Dephosphorylation Regulation Of Protein Transport Positive Regulation Of Dephosphorylation Regulation Of Protein Glycosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Calcium Ion Binding Positive Regulation Of Phospholipid Biosynthetic Process Sodium:proton Antiporter Activity Regulation Of Protein Autophosphorylation Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Negative Regulation Of Protein Import Into Nucleus Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Transport Negative Regulation Of Calcium-mediated Signaling Regulation Of Protein Localization Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Cellular Response To PH Regulation Of Protein Targeting To Membrane Positive Regulation Of Sodium Ion Transport Protein Export From Nucleus
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