CHP2 and SLC9A4

Number of citations of the paper that reports this interaction (PMID 12576672)
8

Data Source:
BioGRID (pull down)

		CHP2	SLC9A4
Gene Name		calcineurin-like EF-hand protein 2	solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Sodium:proton Antiporter Activity
	Biological Process	Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion	Gastric Acid Secretion Epithelial Cell Development Ion Transport Regulation Of PH Sodium Ion Transmembrane Transport Transmembrane Transport Hydrogen Ion Transmembrane Transport
Pathways			Sodium/Proton exchangers Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS			Celiac disease ( 18311140) White blood cell types ( 21738478)
Protein-Protein Interactions		5 interactors: SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5	2 interactors: CHP1 CHP2
Entrez ID		63928	389015
HPRD ID		14259	15973
Ensembl ID		ENSG00000166869	ENSG00000180251
Uniprot IDs		A8K2I8 O43745	Q6AI14
PDB IDs		2BEC
Enriched GO Terms of Interacting Partners?		Regulation Of PH Hydrogen Ion Transmembrane Transport Sodium Ion Transmembrane Transport Proton Transport Sodium Ion Transport Ion Homeostasis Monovalent Inorganic Cation Transport Metal Ion Transport Chemical Homeostasis Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Transport Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Gastric Acid Secretion Maintenance Of Cell Polarity Cellular Response To Electrical Stimulus Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Cellular Response To Antibiotic Cellular Response To Toxic Substance Sodium Ion Homeostasis Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Sensory Perception Of Pain Cellular Response To Catecholamine Stimulus	Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Calcium-mediated Signaling Regulation Of Phosphatase Activity Regulation Of Dephosphorylation Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Transport Positive Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Protein Glycosylation Regulation Of Intracellular Transport Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Acidic PH Negative Regulation Of Calcium-mediated Signaling Regulation Of Protein Transport Regulation Of Protein Glycosylation Regulation Of Establishment Of Protein Localization Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Transport Transcytosis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Proton Transport Hyaluronan Catabolic Process Regulation Of Protein Localization Positive Regulation Of Glycoprotein Biosynthetic Process Cellular Response To PH Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Sodium Ion Transmembrane Transport Response To Acidic PH Regulation Of Cellular Localization Positive Regulation Of Calcium-mediated Signaling Regulation Of Glycoprotein Biosynthetic Process Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Cellular Response To Heat Regulation Of Protein Autophosphorylation Positive Regulation Of Phosphatase Activity Positive Regulation Of Protein Targeting To Membrane Regulation Of Sodium Ion Transmembrane Transport Response To PH Positive Regulation Of Sodium Ion Transport Protein Export From Nucleus Cytoplasmic Microtubule Organization Hyaluronan Metabolic Process Regulation Of Centrosome Duplication
Tagcloud ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover
Tagcloud (Difference) ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover
Tagcloud (Intersection) ?