CHP2 and SLC9A2

Number of citations of the paper that reports this interaction (PMID 12576672)
8

Data Source:
BioGRID (pull down)

		CHP2	SLC9A2
Gene Name		calcineurin-like EF-hand protein 2	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Sodium:proton Antiporter Activity
	Biological Process	Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion	Ion Transport Regulation Of PH Protein Localization Sodium Ion Transmembrane Transport Transmembrane Transport Hydrogen Ion Transmembrane Transport
Pathways			Sodium/Proton exchangers Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5	8 interactors: ABL1 CHP1 CHP2 PIK3R1 RASA1 SPTA1 SPTAN1 SRC
Entrez ID		63928	6549
HPRD ID		14259	02756
Ensembl ID		ENSG00000166869	ENSG00000115616
Uniprot IDs		A8K2I8 O43745	Q9UBY0
PDB IDs		2BEC
Enriched GO Terms of Interacting Partners?		Regulation Of PH Hydrogen Ion Transmembrane Transport Sodium Ion Transmembrane Transport Proton Transport Sodium Ion Transport Ion Homeostasis Monovalent Inorganic Cation Transport Metal Ion Transport Chemical Homeostasis Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Transport Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Gastric Acid Secretion Maintenance Of Cell Polarity Cellular Response To Electrical Stimulus Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Cellular Response To Antibiotic Cellular Response To Toxic Substance Sodium Ion Homeostasis Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Sensory Perception Of Pain Cellular Response To Catecholamine Stimulus	Positive Regulation Of Protein Transport Axon Guidance Regulation Of Organelle Organization Regulation Of Intracellular Transport Negative Regulation Of Cell-matrix Adhesion Regulation Of Cellular Component Organization Regulation Of Cytoskeleton Organization Axonogenesis Negative Regulation Of Cell Adhesion Axon Development Negative Regulation Of Cell-substrate Adhesion Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Locomotion Regulation Of Cell Adhesion Regulation Of Protein Transport Positive Regulation Of Intracellular Transport Neuron Projection Morphogenesis Regulation Of Establishment Of Protein Localization Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Movement Of Cell Or Subcellular Component Regulation Of Protein Localization Neuron Projection Development Regulation Of Protein Complex Assembly Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Actin Cytoskeleton Organization Regulation Of Cell-cell Adhesion Vascular Endothelial Growth Factor Receptor Signaling Pathway Neuron Development Regulation Of Actin Filament-based Process Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Intracellular Signal Transduction Regulation Of Cell-matrix Adhesion Transcytosis Regulation Of Cellular Localization Cell Morphogenesis Negative Regulation Of Protein Complex Assembly Neuron Differentiation Cell Projection Organization Response To Acidic PH Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Import Into Nucleus Regulation Of Actin Filament Polymerization
Tagcloud ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures vwf
Tagcloud (Difference) ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover	actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom ezr fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures vwf
Tagcloud (Intersection) ?