CHP2 and SLC9A2

Number of citations of the paper that reports this interaction (PubMedID 40355756)
172

Data Source:
BioGRID (pull down, affinity chromatography technology)

		CHP2	SLC9A2
Description		calcineurin like EF-hand protein 2	solute carrier family 9 member A2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Plasma Membrane Membrane	Plasma Membrane Membrane Apical Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Antiporter Activity Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Positive Regulation Of Cell Population Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion	Monoatomic Ion Transport Monoatomic Cation Transport Sodium Ion Transport Regulation Of PH Intracellular Protein Localization Epithelial Cell Differentiation Regulation Of Intracellular PH Transmembrane Transport Potassium Ion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport
Pathways			Sodium/Proton exchangers
Drugs
Diseases
GWAS		Daytime nap ( 33568662)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Delirium ( 29631748) Gut microbiota (bacterial taxa) ( 27723756) Night sleep phenotypes ( 27126917) Plateletcrit ( 32888494)
Interacting Genes		6 interacting genes: MDFI SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5	8 interacting genes: ABL1 CHP1 CHP2 PIK3R1 RASA1 SPTA1 SPTAN1 SRC
Entrez ID		63928	6549
HPRD ID		14259	02756
Ensembl ID		ENSG00000166869	ENSG00000115616
Uniprot IDs		O43745	Q9UBY0
PDB IDs		2BEC
Enriched GO Terms of Interacting Partners?		Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity Sodium Ion Import Across Plasma Membrane Regulation Of Cellular PH Regulation Of Intracellular PH Antiporter Activity Inorganic Cation Import Across Plasma Membrane Regulation Of PH Sodium Ion Transmembrane Transport Import Across Plasma Membrane Potassium Ion Transmembrane Transport Proton Transmembrane Transport Potassium Ion Transport Sodium Ion Transport Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Intracellular Chemical Homeostasis Metal Ion Transport Import Into Cell Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Cellular Homeostasis Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Chemical Homeostasis Apical Plasma Membrane Monoatomic Ion Transport Transmembrane Transport Homeostatic Process Recycling Endosome Membrane Regulation Of The Force Of Heart Contraction By Cardiac Conduction Cation-transporting ATPase Complex Regulation Of Biological Quality Transporter Complex Transepithelial Ammonium Transport Positive Regulation Of The Force Of Heart Contraction Glandular Epithelial Cell Development Regulation Of Cardiac Muscle Cell Membrane Potential Protein Phosphatase 2B Binding Neuron Spine Dynactin Complex Gastric Acid Secretion Cardiac Muscle Cell Contraction Positive Regulation Of Action Potential Arrestin Family Protein Binding Cellular Response To Antibiotic Basolateral Plasma Membrane	Regulation Of Actin Filament Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Regulation Of Cell-matrix Adhesion Regulation Of Actin Filament-based Process Regulation Of Dephosphorylation Regulation Of Protein-containing Complex Assembly Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell-matrix Adhesion Phosphotyrosine Residue Binding Substrate Adhesion-dependent Cell Spreading Ephrin Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Regulation Of Cell-substrate Adhesion Regulation Of Protein Import Into Nucleus Regulation Of Organelle Organization Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Dephosphorylation Regulation Of Intracellular Transport Regulation Of Cell-substrate Junction Organization Negative Regulation Of Cell Adhesion Spectrin Regulation Of Phosphatase Activity Positive Regulation Of Protein Localization To Nucleus Regulation Of Cell Adhesion Regulation Of Biological Quality Actin Cytoskeleton Organization Regulation Of Nucleocytoplasmic Transport Actin Filament-based Process Regulation Of Actin Filament Polymerization Plasma Membrane Negative Regulation Of Protein-containing Complex Assembly Positive Regulation Of Protein Localization Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Intracellular Protein Transport Cell Activation Involved In Immune Response Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Cell-substrate Adhesion Leukocyte Activation Involved In Immune Response Supramolecular Fiber Organization Negative Regulation Of Supramolecular Fiber Organization Negative Regulation Of Cytoskeleton Organization Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Localization Regulation Of Intracellular Signal Transduction Regulation Of Catalytic Activity Ephrin Receptor Binding
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