CHP2 and SLC9A5

Number of citations of the paper that reports this interaction (PMID 12576672)
8

Data Source:
BioGRID (pull down)

		CHP2	SLC9A5
Gene Name		calcineurin-like EF-hand protein 2	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding	Sodium:proton Antiporter Activity
	Biological Process	Positive Regulation Of Cell Proliferation Positive Regulation Of Phosphatase Activity Protein Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Calcium Ion	Transport Ion Transport Regulation Of PH Sodium Ion Transmembrane Transport Transmembrane Transport Hydrogen Ion Transmembrane Transport
Pathways			Sodium/Proton exchangers Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5	4 interactors: ARRB1 ARRB2 CHP1 CHP2
Entrez ID		63928	6553
HPRD ID		14259	02723
Ensembl ID		ENSG00000166869	ENSG00000135740
Uniprot IDs		A8K2I8 O43745	Q14940 Q9NSW9
PDB IDs		2BEC
Enriched GO Terms of Interacting Partners?		Regulation Of PH Hydrogen Ion Transmembrane Transport Sodium Ion Transmembrane Transport Proton Transport Sodium Ion Transport Ion Homeostasis Monovalent Inorganic Cation Transport Metal Ion Transport Chemical Homeostasis Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Sodium Ion Import Across Plasma Membrane Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Transport Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Positive Regulation Of Calcineurin-NFAT Signaling Cascade Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Gastric Acid Secretion Maintenance Of Cell Polarity Cellular Response To Electrical Stimulus Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Cellular Response To Epinephrine Stimulus Response To Acidic PH Positive Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Mitochondrial Membrane Permeability Response To Epinephrine Cellular Response To Antibiotic Cellular Response To Toxic Substance Sodium Ion Homeostasis Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Sensory Perception Of Pain Cellular Response To Catecholamine Stimulus	Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Protein Ubiquitination Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Transport Regulation Of Calcineurin-NFAT Signaling Cascade G-protein Coupled Receptor Internalization Regulation Of Protein Ubiquitination Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Receptor Internalization Regulation Of Receptor Internalization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Protein Transport Protein Transport Negative Regulation Of Interleukin-6 Production Positive Regulation Of Receptor-mediated Endocytosis Establishment Of Protein Localization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Hydrolase Activity Receptor Internalization Regulation Of Calcium-mediated Signaling Positive Regulation Of Cellular Biosynthetic Process Regulation Of Intracellular Signal Transduction Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Receptor Metabolic Process Regulation Of Protein Transport Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Establishment Of Protein Localization Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Regulation Of Phosphatase Activity Regulation Of Interleukin-6 Production Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Endocytosis Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Dephosphorylation Regulation Of Signal Transduction Notch Signaling Pathway Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Organelle Organization Regulation Of Protein Binding Positive Regulation Of Intracellular Protein Transport
Tagcloud ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover
Tagcloud (Difference) ?		asf1 assemble associate boundary chaperone clr6 concert deacetylases deacetylation enforce fission hdac hdacs heterochromatic heterochromatin hira hp1 nucleosome occupancy recruiting repressive shrec silence silenced snf2 spreads swi6 tfiiic uncover
Tagcloud (Intersection) ?