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SLC6A9 and STX1A
Number of citations of the paper that reports this interaction (PMID
10722844
)
7
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(in vivo)
SLC6A9
STX1A
Gene Name
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
syntaxin 1A (brain)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Extracellular Region
Cytosol
Plasma Membrane
Synaptic Vesicle
Endomembrane System
Integral Component Of Membrane
Cell Junction
Secretory Granule
Synaptic Vesicle Membrane
SNARE Complex
Actomyosin
Neuron Projection
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex
Synaptobrevin 2-SNAP-25-syntaxin-1a Complex
Molecular Function
Neurotransmitter:sodium Symporter Activity
Glycine:sodium Symporter Activity
SNARE Binding
Glycoprotein Binding
SNAP Receptor Activity
Protein Binding
Myosin Binding
Calcium Channel Inhibitor Activity
Chloride Channel Inhibitor Activity
Kinase Binding
Protein Domain Specific Binding
Protein Binding, Bridging
Myosin Head/neck Binding
ATP-dependent Protein Binding
Protein Heterodimerization Activity
Protein N-terminus Binding
Calcium-dependent Protein Binding
Biological Process
Amino Acid Transmembrane Transport
Transport
Neurotransmitter Transport
Glycine Transport
Transmembrane Transport
Positive Regulation Of Neurotransmitter Secretion
Energy Reserve Metabolic Process
Intracellular Protein Transport
Synaptic Transmission
Neurotransmitter Secretion
Pathogenesis
Response To Gravity
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Synaptic Vesicle Docking
Calcium Ion-dependent Exocytosis
Synaptic Vesicle Fusion To Presynaptic Membrane
Secretion By Cell
Cellular Protein Metabolic Process
Small Molecule Metabolic Process
Positive Regulation Of Exocytosis
Vesicle Docking
Regulation Of Insulin Secretion
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Na+/Cl- dependent neurotransmitter transporters
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
SLC-mediated transmembrane transport
Dopamine Neurotransmitter Release Cycle
Integration of energy metabolism
Acetylcholine Neurotransmitter Release Cycle
Regulation of insulin secretion
Toxicity of botulinum toxin type C (BoNT/C)
Norepinephrine Neurotransmitter Release Cycle
GABA synthesis, release, reuptake and degradation
Glutamate Neurotransmitter Release Cycle
Peptide hormone metabolism
Uptake and actions of bacterial toxins
Neurotransmitter Release Cycle
Insulin processing
Serotonin Neurotransmitter Release Cycle
Neurotoxicity of clostridium toxins
Transmission across Chemical Synapses
Drugs
Glycine
Diseases
GWAS
Protein-Protein Interactions
3 interactors:
GABRR1
PRKCA
STX1A
58 interactors:
ABCC9
APBA1
ATP4B
ATP6V1B1
CACNA1D
CCSER2
CDK5
CFTR
CPLX1
CSNK2A1
CSNK2A2
DAPK1
KCNB1
NAPA
NAPB
NSF
PSMA3
RAB27A
RIMS1
SCNN1A
SCNN1B
SCNN1G
SDCBP
SEPT2
SEPT5
SLC6A1
SLC6A2
SLC6A3
SLC6A4
SLC6A5
SLC6A9
SNAP23
SNAP25
SNAP29
SNPH
STX8
STXBP1
STXBP2
STXBP5
STXBP6
SUMO1P1
SYT1
SYT4
SYT7
SYTL4
TRDMT1
TXLNA
TXLNB
UNC13B
VAMP1
VAMP2
VAMP5
VAMP7
VAMP8
VAPB
VIM
VPS11
VPS18
Entrez ID
6536
6804
HPRD ID
03010
01721
Ensembl ID
ENSG00000196517
ENSG00000106089
Uniprot IDs
B7Z3W8
P48067
A8MZ54
Q16623
Q75ME0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Synaptic Transmission
Cell-cell Signaling
Energy Reserve Metabolic Process
Positive Regulation Of Dense Core Granule Biogenesis
Regulation Of Insulin Secretion
Histone H3-T6 Phosphorylation
Regulation Of Peptide Hormone Secretion
Regulation Of Hormone Secretion
Energy Derivation By Oxidation Of Organic Compounds
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Regulation Of Protein Secretion
Generation Of Precursor Metabolites And Energy
Regulation Of Synaptic Vesicle Priming
Synaptic Vesicle Docking
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Synaptic Vesicle Fusion To Presynaptic Membrane
Negative Regulation Of Glucose Import
Positive Regulation Of Macrophage Differentiation
Desmosome Organization
Response To Gravity
Positive Regulation Of Neurotransmitter Secretion
Regulation Of Protein Transport
Regulation Of Platelet Aggregation
Negative Regulation Of Glucose Transport
Regulation Of Secretion
Induction Of Positive Chemotaxis
Positive Regulation Of Cardiac Muscle Hypertrophy
Anion Transport
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Establishment Of Protein Localization
Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Lyase Activity
Glutamate Secretion
Regulation Of Rhodopsin Mediated Signaling Pathway
Regulation Of Protein Localization
Negative Regulation Of CAMP Biosynthetic Process
Activation Of Adenylate Cyclase Activity
Regulation Of Cardiac Muscle Hypertrophy
Rhodopsin Mediated Signaling Pathway
Gamma-aminobutyric Acid Signaling Pathway
Regulation Of Platelet Activation
Membrane Organization
Positive Regulation Of Positive Chemotaxis
Negative Regulation Of CAMP Metabolic Process
Regulation Of The Force Of Heart Contraction
Inactivation Of MAPK Activity
Regulation Of Synaptic Vesicle Exocytosis
Exocytosis
Secretion By Cell
Neurotransmitter Transport
Secretion
Regulation Of Exocytosis
Regulation Of Neurotransmitter Levels
Transport
Vesicle-mediated Transport
Regulation Of Secretion
Neurotransmitter Secretion
Synaptic Transmission
Cell-cell Signaling
Regulation Of Vesicle-mediated Transport
Establishment Of Localization In Cell
Synaptic Vesicle Transport
Synaptic Vesicle Exocytosis
Cellular Localization
Positive Regulation Of Exocytosis
Regulation Of Cellular Localization
Membrane Fusion
Glutamate Secretion
Establishment Of Vesicle Localization
Vesicle Localization
Ion Transport
Vesicle Fusion
Protein Transport
Establishment Of Protein Localization
Amino Acid Transport
Vesicle Docking
Organelle Fusion
Membrane Docking
Establishment Of Organelle Localization
Membrane Organization
Acid Secretion
Vesicle Organization
Positive Regulation Of Secretion
Organelle Localization
Protein Localization
Monovalent Inorganic Cation Transport
Anion Transport
Dicarboxylic Acid Transport
Regulated Secretory Pathway
Metal Ion Transport
Vesicle Docking Involved In Exocytosis
Positive Regulation Of Transport
Carboxylic Acid Transport
Regulation Of Synaptic Transmission
Organic Acid Transport
Sodium Ion Transport
Organic Anion Transport
Tagcloud
?
colitis
colonized
died
h7
hemolytic
hemorrhagic
hus
isogenic
k3995
lysogenic
o157
outbreak
outbreaks
phage
phages
rabbits
reflects
shiga
spinach
stec
streptomycin
stx2
stx2a
stx2c
succumbed
toxin
uremic
virulence
Tagcloud (Difference)
?
colitis
colonized
died
h7
hemolytic
hemorrhagic
hus
isogenic
k3995
lysogenic
o157
outbreak
outbreaks
phage
phages
rabbits
reflects
shiga
spinach
stec
streptomycin
stx2
stx2a
stx2c
succumbed
toxin
uremic
virulence
Tagcloud (Intersection)
?