MCC and MSANTD3

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		MCC	MSANTD3
Description		MCC regulator of Wnt signaling pathway	Myb/SANT DNA binding domain containing 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Lamellipodium Cell Projection
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding
	Biological Process	Signal Transduction Negative Regulation Of Epithelial Cell Migration Wnt Signaling Pathway Establishment Of Protein Localization Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Brain cytoarchitecture ( 20308991) Cerebral amyloid angiopathy ( 25188341) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 31562340) Metabolite levels ( 23823483) Neurofibrillary tangles ( 31497858) Nicotine dependence symptom count ( 25555482) Triglyceride levels ( 32203549) Waist circumference adjusted for body mass index ( 34021172)	Conjunctival UV autofluorescence (CUVAF) ( 25590795)
Interacting Genes		77 interacting genes: ALDOB ANP32B APP BAAT C8orf33 C8orf48 CBX5 CBX8 CCDC112 CCDC146 CCDC180 CCDC185 CCDC187 CDC14B CDK8 CDKL3 CEP57L1 CEP95 CFAP58 CYLC2 DNAAF4 DYNC1I1 ELOA ERBIN ESRRG FAM161A FGF16 FRAT2 GTF2E2 HEMGN HSD17B3 KAT5 KEAP1 KIF3C KIFC3 LRRC45 MSANTD3 MTNR1A NANS NEK2 NFKBIB NOL12 PCCA PNKP POLL PRPF18 RASAL2 RCOR3 SEC61B SFRP4 SLTM SLU7 SYT17 SYT6 TCEA2 TCEANC TGFB1 THAP7 TRMO TRMT2A TSHZ2 TSTD2 TXLNA UTP14C ZBTB48 ZNF12 ZNF189 ZNF202 ZNF264 ZNF3 ZNF35 ZNF417 ZNF438 ZNF497 ZNF543 ZNF648 ZNF792	16 interacting genes: BMPR1A BUB1 CDH1 FXR1 FXR2 GNAS MCC MLH3 MUTYH PFN2 SMAD4 SUV39H1 TMEM129 TSC1 VSTM2A ZDHHC17
Entrez ID		4163	91283
HPRD ID		01157	14459
Ensembl ID		ENSG00000171444	ENSG00000066697
Uniprot IDs		P23508	Q96H12
PDB IDs		6MTU 6MTV
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Centrosome	Cellular Response To BMP Stimulus Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Presynaptic Modulation Of Chemical Synaptic Transmission Mesendoderm Development Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Multicellular Organismal Process Postsynapse Modulation Of Chemical Synaptic Transmission Cardiac Conduction System Development Negative Regulation Of Epithelial Cell Migration Translation Regulator Activity Animal Organ Development Regulation Of Growth Regulation Of Developmental Growth Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Regulation Of Cell Communication Regulation Of Signaling Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Locomotion Outflow Tract Septum Morphogenesis Regulation Of Neurogenesis Mismatch Repair Positive Regulation Of Cellular Component Organization Pituitary Gland Development Endoderm Development Regulation Of Multicellular Organismal Process Regulation Of Neural Crest Cell Differentiation Regulation Of Cellular Component Organization Regulation Of Cellular Senescence Ventricular Septum Morphogenesis Regulation Of Cell Development Regulation Of Developmental Process SMAD Binding Ventricular Cardiac Muscle Tissue Morphogenesis Neural Plate Mediolateral Regionalization Paraxial Mesoderm Structural Organization Positive Regulation Of Cell Differentiation Fibrous Ring Of Heart Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction Regulation Of Nervous System Development Positive Regulation Of Cardiac Ventricle Development Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Histone H2A Kinase Activity Lamellipodium Cardiocyte Differentiation Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
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