MRPL44 and NGEF

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		MRPL44	NGEF
Description		mitochondrial ribosomal protein L44	neuronal guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit Ribosome Plasma Membrane Nuclear Body Ribonucleoprotein Complex	Cytoplasm Cytosol Membrane Growth Cone Cell Projection Glutamatergic Synapse
	Molecular Function	RNA Binding Double-stranded RNA Binding Nuclease Activity Endonuclease Activity Ribonuclease III Activity Protein Binding Hydrolase Activity	Guanyl-nucleotide Exchange Factor Activity Protein Binding Ephrin Receptor Binding
	Biological Process	RNA Processing Mitochondrial Translation Mitochondrial Translational Elongation	Nervous System Development Cell Differentiation Regulation Of Actin Cytoskeleton Organization Regulation Of GTPase Activity Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Dendritic Spine Morphogenesis Regulation Of Synapse Pruning
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control	NRAGE signals death through JNK EPHA-mediated growth cone collapse EPHA-mediated growth cone collapse G alpha (12/13) signalling events RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Contrast sensitivity ( 24152035) Heel bone mineral density ( 28869591 30598549) Parkinson's disease ( 32201043) Pursuit maintenance gain ( 29064472) Schizophrenia ( 23974872 25056061 28991256 29483656 30285260) Sudden cardiac arrest ( 30169657) Superior temporal sulcus banks volume ( 31530798)
Interacting Genes		21 interacting genes: ABI2 CEP70 DGKE DMRTB1 IMMT ITFG1 KRT31 NGEF PI4KA PLPP2 PRPF6 PRRC2B PTN QKI RBPMS SEMA5B SETDB1 SHC1 USP22 VIM ZNF235	16 interacting genes: ATP5F1C C7orf25 C8orf33 EPHA4 FAM118B HCK LCOR MRPL44 NUDT21 RHOA SH2D1A SMO TAF1D TRIM55 TRIM63 USP7
Entrez ID		65080	25791
HPRD ID		14763	10442
Ensembl ID		ENSG00000135900	ENSG00000066248
Uniprot IDs		Q9H9J2	B4DDI2 Q8N5V2
PDB IDs		3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QH6 7QH7 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?
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