PLEKHG2 and CDC42

  • Number of citations of the paper that reports this interaction (PMID 11839748)
  • 5
  • Data Source:
  • HPRD (in vitro)

PLEKHG2

CDC42

Gene Name pleckstrin homology domain containing, family G (with RhoGef domain) member 2 cell division cycle 42
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune response to smallpox vaccine (IL-6) ( 22610502)
Protein-Protein Interactions 8 interactors: ACTN3 APP CDC42 GNB1 GNG2 RAC1 RHOA XRN1 144 interactors: A2M ACTR3 AHSG ANXA2 APOH ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP31 ARHGAP32 ARHGAP44 ARHGDIA ARHGDIB ARHGDIG ARHGEF11 ARHGEF25 ARHGEF6 ARHGEF7 ARRB1 ARRB2 BAIAP2 BCR BNIP2 BNIPL C14orf1 CASP3 CASP7 CBLL1 CDC42BPA CDC42BPB CDC42BPG CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDC42SE1 CDC42SE2 CDH1 CDKN1A CFHR4 CNTNAP1 COX1 CPN1 CSN2 CSPG4 DEF6 DIAPH2 DIAPH3 DOCK7 DOCK8 DOCK9 EEF1G EIF2AK2 ERRFI1 ETFA FGD1 FGD3 FLNA FMNL2 FNBP1 GDI1 GOPC GRB2 HERC2 IQGAP1 IQGAP2 ITSN1 KAT5 KIAA2026 KTN1 LCK LGALS1 LRIF1 MAP3K10 MAP3K11 MAP3K4 MARK4 MCF2 MCF2L MCM3AP METAP2 MUC12 MYO6 MYO9A NCF2 NEK6 OCRL OPHN1 PAK1 PAK2 PAK3 PAK4 PAK6 PAK7 PARD3 PARD6A PARD6B PARD6G PDE6D PGGT1B PIK3R1 PLD1 PLEKHG2 PRKCA PRKCG PRKCI PRKCZ RAC1 RAC2 RAP1GDS1 RHOJ RIOK3 RPL22 RPL23 RPS6KB1 S100A9 SH3D19 SRGAP1 SSX2IP ST13 STAU1 SYNE1 TBC1D3F TNK2 TP53 TRAF2 TRIP10 UBR1 UNC119 USP6 VAV1 VRK2 WAS WASF1 WASF2 WASL WIPF1 ZNF175 ZNF234 ZNF420
Entrez ID 64857 998
HPRD ID 15148 00309
Ensembl ID ENSG00000090924 ENSG00000070831
Uniprot IDs E7ESZ3 Q9H7P9 B4E1U9 E7ETU3 P60953
PDB IDs 1A4R 1AJE 1AM4 1AN0 1CEE 1CF4 1DOA 1E0A 1EES 1GRN 1GZS 1KI1 1KZ7 1KZG 1NF3 2ASE 2DFK 2KB0 2NGR 2ODB 2QRZ 2WM9 2WMN 2WMO 3GCG 3QBV 3VHL 4DID 4ITR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
abl1  candidates  cdc42  constitutively  csrc  cytoskeletal  ephrinb2  flj00018  gbetagamma  gtp  guanine  hek293  heterotrimeric  homology  kinse  mutagenesis  partner  phosphorylated  pik3r3  rac  reorganization  rho  rhogef  sh2  substitution  throughput  turn  tyr489  tyrosine 
abolished  adapter  adjacent  autophosphorylation  coprecipitate  coprecipitation  detailed  explained  fragment  gtpase  hck  homology  identity  modeling  mutational  nak  nck  nef  p21  pak  paks  plasmon  resonance  sh3  src  subset  termed  threonine  uncertain 
Tagcloud (Difference) ?
abl1  candidates  constitutively  csrc  cytoskeletal  ephrinb2  flj00018  gbetagamma  gtp  guanine  hek293  heterotrimeric  kinse  mutagenesis  partner  phosphorylated  pik3r3  rac  reorganization  rho  rhogef  sh2  substitution  throughput  turn  tyr489  tyrosine 
abolished  adapter  adjacent  autophosphorylation  coprecipitate  coprecipitation  detailed  explained  fragment  gtpase  hck  identity  modeling  mutational  nak  nck  nef  p21  pak  paks  plasmon  resonance  sh3  src  subset  termed  threonine  uncertain 
Tagcloud (Intersection) ?
cdc42  homology