ATG3 and GABARAP

Number of citations of the paper that reports this interaction (PMID 11825910)
49

Data Source:
HPRD (in vitro, in vivo)

		ATG3	GABARAP
Gene Name		autophagy related 3	GABA(A) receptor-associated protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Ubiquitin Ligase Complex Cytosol	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Protein Modification Process Protein Targeting To Membrane Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Nucleophagy Regulation Of Cilium Assembly	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATG12 ATG5 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3A MAP1LC3B	29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28
Entrez ID		64422	11337
HPRD ID		10654	05496
Ensembl ID		ENSG00000144848
Uniprot IDs		Q9NT62	O95166 Q6IAW1
PDB IDs			1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Nucleophagy Cellular Response To Nitrogen Starvation Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Cellular Response To Starvation Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Extracellular Stimulus Vacuole Organization Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Organization Organelle Assembly Membrane Fusion Cellular Response To Stress Catabolic Process Response To External Stimulus C-terminal Protein Lipidation Negative Regulation Of Histone H4-K16 Acetylation Organelle Organization Cellular Component Assembly Response To Stress Negative Regulation Of Histone H4 Acetylation Negative Stranded Viral RNA Replication Membrane Organization Protein Lipidation Regulation Of Histone H4 Acetylation Positive Regulation Of Mucus Secretion Lipoprotein Biosynthetic Process Positive Regulation Of Macroautophagy Regulation Of Mucus Secretion Negative Regulation Of Histone Acetylation Cell Communication Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Viral Genome Replication Lipoprotein Metabolic Process Post-translational Protein Modification Cellular Response To Stimulus Positive Regulation Of Autophagy Regulation Of Histone Acetylation Negative Regulation Of Type I Interferon Production Cardiac Muscle Cell Development Response To Stimulus Cellular Response To Aluminum Ion Negative Regulation Of Chromosome Organization Regulation Of Type I Interferon Production	Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation
Tagcloud ?		alkaloids anticancer araguspongine araguspongines atg16l atg7 autophagic autophagy bt cascade docking dysregulations inositol kinases lc3a lyte macrocyclic marine met overexpressing oxaquinolizidine remarkably silico sponge trisphosphate tyrosine vacuole xestospongia xestospongin	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		alkaloids anticancer araguspongine araguspongines atg16l bt cascade docking dysregulations inositol kinases lc3a lyte macrocyclic marine met overexpressing oxaquinolizidine remarkably silico sponge trisphosphate tyrosine vacuole xestospongia xestospongin	akt1 antipsychotic atg atg12 atg4b atg5 autophagosome autophagosomes bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?		atg7 autophagic autophagy