DCLRE1C and DDB2

Number of citations of the paper that reports this interaction (PMID 22134138)
6

Data Source:
BioGRID (pull down)

		DCLRE1C	DDB2
Gene Name		DNA cross-link repair 1C	damage-specific DNA binding protein 2, 48kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm Cell Junction Cul4B-RING E3 Ubiquitin Ligase Complex Protein Complex
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity 5'-3' Exonuclease Activity	DNA Binding Damaged DNA Binding Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Telomere Maintenance DNA Catabolic Process, Endonucleolytic Double-strand Break Repair Response To Ionizing Radiation B Cell Differentiation V(D)J Recombination Nucleic Acid Phosphodiester Bond Hydrolysis	Protein Polyubiquitination Nucleotide-excision Repair, DNA Damage Removal DNA Repair Nucleotide-excision Repair Pyrimidine Dimer Repair Response To UV Histone H2A Monoubiquitination Protein Autoubiquitination UV-damage Excision Repair
Pathways			Nucleotide Excision Repair Global Genomic NER (GG-NER) Formation of incision complex in GG-NER Dual incision reaction in GG-NER
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ATM ATR BRCA1 DDB1 DDB2 MRE11A NBN PRKDC PSMD9 RAD50 TP53BP1	15 interactors: ABL1 CUL4A CUL4B DCLRE1C DDB1 E2F1 HDAC1 HIST2H2AC HIST2H3C NTMT1 TOP1 USP24 USP40 XPA XPC
Entrez ID		64421	1643
HPRD ID		05817	02886
Ensembl ID		ENSG00000152457	ENSG00000134574
Uniprot IDs		B3KMX5 Q96SD1	Q92466
PDB IDs		3W1B 3W1G 4HTP	3EI4 3I7L 4E54 4E5Z
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To Stress DNA Damage Checkpoint DNA Metabolic Process Cell Cycle Checkpoint Telomere Maintenance Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Response To Stress G2 DNA Damage Checkpoint Cell Cycle Process Mitotic Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Cell Cycle Response To Radiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Autophosphorylation Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Mitotic G2 DNA Damage Checkpoint Chromosome Organization Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Protein Autophosphorylation Regulation Of Cellular Protein Metabolic Process Response To Ionizing Radiation DNA Catabolic Process Cellular Response To Radiation Organelle Organization Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process Heterocycle Metabolic Process Reciprocal Meiotic Recombination Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Response To Gamma Radiation Meiotic Cell Cycle Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint	DNA Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process DNA Repair Regulation Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Catabolic Process Regulation Of Cell Cycle Cellular Response To Stress Response To UV DNA Catabolic Process Intrinsic Apoptotic Signaling Pathway Response To Radiation Response To Stress UV-damage Excision Repair Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization Histone H2A Monoubiquitination Nucleotide-excision Repair Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Abiotic Stimulus Histone H2A Ubiquitination Response To Light Stimulus Positive Regulation Of Mitotic Cell Cycle Apoptotic Signaling Pathway Nitrogen Compound Metabolic Process Cellular Metabolic Process Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Histone Monoubiquitination Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Aromatic Compound Catabolic Process Negative Regulation Of Cell Cycle Interaction With Symbiont
Tagcloud ?		alleles breakpoints carrier casp3 catabolism cdh19 centered cnv cnvs cyp2c19 cyp450 dab2ip deletion differed disrupted disturbed encodes estradiol exact finnish inherited itga9 multiplex nested northern participating qpcr singletons unselected	adherens bioassays bladder carcinogenic carcinogens chemicals consistently construct discriminate evaluating foundation gadd45a genotoxic genotoxicity globaltest hepg2 implemented industry investigating junction microarrays pam peroxisome perturbation pharmaceutical rrm2b set sets validate
Tagcloud (Difference) ?		alleles breakpoints carrier casp3 catabolism cdh19 centered cnv cnvs cyp2c19 cyp450 dab2ip deletion differed disrupted disturbed encodes estradiol exact finnish inherited itga9 multiplex nested northern participating qpcr singletons unselected	adherens bioassays bladder carcinogenic carcinogens chemicals consistently construct discriminate evaluating foundation gadd45a genotoxic genotoxicity globaltest hepg2 implemented industry investigating junction microarrays pam peroxisome perturbation pharmaceutical rrm2b set sets validate
Tagcloud (Intersection) ?