DCLRE1C

Gene Name		DNA cross-link repair 1C
Image
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity 5'-3' Exonuclease Activity
	Biological Process	Telomere Maintenance DNA Catabolic Process, Endonucleolytic Double-strand Break Repair Response To Ionizing Radiation B Cell Differentiation V(D)J Recombination Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		11 interactors: ATM ATR BRCA1 DDB1 DDB2 MRE11A NBN PRKDC PSMD9 RAD50 TP53BP1
Entrez ID		64421
HPRD ID		05817
Ensembl ID		ENSG00000152457
Uniprot IDs		B3KMX5 Q96SD1
PDB IDs		3W1B 3W1G 4HTP
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Double-strand Break Repair DNA Repair DNA Recombination Cellular Response To Stress DNA Damage Checkpoint DNA Metabolic Process Cell Cycle Checkpoint Telomere Maintenance Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Mitotic DNA Integrity Checkpoint Response To Stress G2 DNA Damage Checkpoint Cell Cycle Process Mitotic Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Cell Cycle Response To Radiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Protein Autophosphorylation Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process Mitotic G2 DNA Damage Checkpoint Chromosome Organization Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Protein Autophosphorylation Regulation Of Cellular Protein Metabolic Process Response To Ionizing Radiation DNA Catabolic Process Cellular Response To Radiation Organelle Organization Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Cellular Response To Stimulus Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process Heterocycle Metabolic Process Reciprocal Meiotic Recombination Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Response To Gamma Radiation Meiotic Cell Cycle Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Tagcloud ?		alleles breakpoints carrier casp3 catabolism cdh19 centered cnv cnvs cyp2c19 cyp450 dab2ip deletion differed disrupted disturbed encodes estradiol exact finnish inherited itga9 multiplex nested northern participating qpcr singletons unselected