FAM25C and SNX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM25C	SNX1
Description		family with sequence similarity 25 member C	sorting nexin 1
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Lysosome Endosome Early Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Lamellipodium Retromer Complex Retromer, Tubulation Complex Early Endosome Membrane Vesicle Protein-containing Complex Cell Projection
	Molecular Function		Epidermal Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding Lipid Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Transferrin Receptor Binding Leptin Receptor Binding
	Biological Process		Intracellular Protein Transport Protein Transport Endosomal Transport Receptor Internalization Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process Lamellipodium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Pancreas fat ( 34128465)
Interacting Genes		18 interacting genes: ARMC10 ARMCX3 COX16 GPD1 IGLL1 KLHL35 LCN1 LCN2 MIEF1 MIEF2 PPIC PPIF S100A6 SNX1 TDRKH TOMM20L TTPA ZFAND3	49 interacting genes: ACVR1B ACVR2B AGTRAP APP ARFIP2 ARL6IP1 ARMC12 ATXN7 CCDC148 CHRNG CMTM4 CMTM5 COQ3 EGFR F2R FAM25A FAM25C FAM25G FKBP7 FUNDC1 HCCS HGS INSR LEPR LIME1 MPC2 NRIP1 PDGFRB PLIN3 RABAC1 REEP5 REEP6 RHEX RTN3 RTN4 SASH1 SDCBP SDR16C5 SFT2D1 SH3GLB1 SNCA SNX2 SNX6 SYNGR1 SYP TK1 TMEM239 UFD1 VPS35
Entrez ID		644054	6642
HPRD ID		19638	03171
Ensembl ID		ENSG00000276430	ENSG00000028528
Uniprot IDs		B3EWG5	Q13596
PDB IDs			2I4K 4FZS 8A1G 8ABQ 8AFZ
Enriched GO Terms of Interacting Partners?		Mitochondrial Outer Membrane Cyclosporin A Binding Regulation Of Mitochondrion Organization Mitochondrion Mitochondrion Organization Positive Regulation Of Mitochondrial Fission Mitochondrial Fusion Small Molecule Binding Positive Regulation Of Protein Targeting To Membrane Regulation Of Mitochondrial Fission Regulation Of Protein Targeting To Membrane Peptidyl-prolyl Cis-trans Isomerase Activity Glycerol-3-phosphate Dehydrogenase (NAD+) Activity Positive Regulation Of Hippocampal Neuron Apoptotic Process Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Proton-transporting ATPase Activity, Rotational Mechanism Glycerol-3-phosphate Dehydrogenase [NAD(P)+] Activity Glycerol-3-phosphate Catabolic Process Glycerol-3-phosphate Shuttle Positive Regulation Of Iron Ion Import Across Plasma Membrane Enterobactin Binding Positive Regulation Of Endothelial Tube Morphogenesis Iron Ion Sequestering Activity Positive Regulation Of Growth Rate TRNA Import Into Mitochondrion Cellular Response To Hydrogen Peroxide	Membrane Endoplasmic Reticulum Membrane Organization Endoplasmic Reticulum Tubular Network Formation Cellular Response To Growth Factor Stimulus Receptor Complex Regulation Of Long-term Neuronal Synaptic Plasticity Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Membrane Organization Response To Growth Factor Positive Regulation Of Locomotion Positive Regulation Of Cell Migration PTB Domain Binding Regulation Of Neuronal Synaptic Plasticity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Vesicle-mediated Transport Regulation Of Transport Retromer Complex Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Cell Motility Activin Receptor Activity Cell Migration Involved In Vasculogenesis Retromer, Tubulation Complex Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Lysosome Identical Protein Binding Membrane Organization Positive Regulation Of Transport Positive Regulation Of Activin Receptor Signaling Pathway Cytoplasmic Vesicle Tubular Endosome Activin Receptor Complex Regulation Of Locomotion Establishment Of Protein Localization Synapse Early Endosome Membrane Cadherin Binding Regulation Of Synaptic Plasticity Positive Regulation Of MAPK Cascade Neuron Projection Activin Binding Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Calcium Ion Transport Transmembrane Receptor Protein Tyrosine Kinase Activity Modulation Of Chemical Synaptic Transmission Transmembrane Receptor Protein Serine/threonine Kinase Activity
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