UBTFL1 and ZBTB7B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBTFL1	ZBTB7B
Description		upstream binding transcription factor like 1	zinc finger and BTB domain containing 7B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity DNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Blastocyst Growth Transcription By RNA Polymerase I Embryo Implantation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase I	Negative Regulation Of Transcription By RNA Polymerase II NK T Cell Differentiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Ectoderm Development Lactation Regulation Of Gene Expression Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Interleukin-17 Production Response To Insulin Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Regulation Of T-helper Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of NK T Cell Proliferation Positive Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cold-induced Thermogenesis Adaptive Thermogenesis Negative Regulation Of T-helper 17 Cell Differentiation Positive Regulation Of SREBP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	A body shape index ( 34021172) Adult body size ( 32376654) Basal cell carcinoma ( 31174203) Bipolar disorder ( 31043756) Birth weight ( 27680694) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 34021172) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 31604244) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		30 interacting genes: BEND3 C3orf36 CCDC136 CDR2 DDIT4L FSD2 GOLGA2 GOLGA6L9 LBX1 LDOC1 LHX2 LHX3 LHX9 MTUS2 NACC1 NOTO OR4F16 OR4F29 OR4F3 OR5AS1 PBX4 PUF60 RABEP1 RUNDC3A STX1A TAX1BP1 TFIP11 ZBTB7B ZCCHC9 ZNF558	27 interacting genes: BCL6 BCL6B CCNL2 CRBN EP300 FAM90A1 GRAP2 GRB2 IMP4 KPNA2 MORF4L2 NCK2 NDN OSTF1 PIN1 RELA RPL9 SH3KBP1 SH3YL1 SORBS3 SYTL4 TRIP10 UBTFL1 ZBTB42 ZBTB5 ZNF277 ZSCAN5B
Entrez ID		642623	51043
HPRD ID			09625
Ensembl ID		ENSG00000255009	ENSG00000160685
Uniprot IDs		P0CB47	O15156
PDB IDs
Enriched GO Terms of Interacting Partners?		Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell Olfactory Receptor Activity Sensory Perception Of Smell Detection Of Chemical Stimulus Involved In Sensory Perception Detection Of Chemical Stimulus Sensory Perception Of Chemical Stimulus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Detection Of Stimulus Involved In Sensory Perception Dorsal/ventral Pattern Formation Neuron Differentiation DNA Binding	Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process Intracellular Signaling Cassette Regulation Of RNA Metabolic Process Phosphotyrosine Residue Binding Negative Regulation Of RNA Biosynthetic Process Type 2 Immune Response Negative Regulation Of DNA-templated Transcription Positive Regulation Of Leukocyte Cell-cell Adhesion Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Negative Regulation Of RNA Metabolic Process Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Activation Chromatin DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of T Cell Activation SH3 Domain Binding Small GTPase-mediated Signal Transduction DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Nucleoplasm DNA Binding Negative Regulation Of Mitotic Cell Cycle DNA Replication Regulation Of Lymphocyte Activation Positive Regulation Of Cell Adhesion Regulation Of DNA Recombination Regulation Of Cell-cell Adhesion Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity NF-kappaB Binding Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Endodermal Cell Differentiation Guanyl-nucleotide Exchange Factor Adaptor Activity Vesicle Membrane Non-canonical NF-kappaB Signal Transduction Cis-trans Isomerase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?