UBTFL1 and NOTO

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBTFL1	NOTO
Description		upstream binding transcription factor like 1	notochord homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity DNA Binding Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Blastocyst Growth Transcription By RNA Polymerase I Embryo Implantation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase I	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Brain Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly
Pathways			Formation of axial mesoderm
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)
Interacting Genes		30 interacting genes: BEND3 C3orf36 CCDC136 CDR2 DDIT4L FSD2 GOLGA2 GOLGA6L9 LBX1 LDOC1 LHX2 LHX3 LHX9 MTUS2 NACC1 NOTO OR4F16 OR4F29 OR4F3 OR5AS1 PBX4 PUF60 RABEP1 RUNDC3A STX1A TAX1BP1 TFIP11 ZBTB7B ZCCHC9 ZNF558	31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1
Entrez ID		642623	344022
HPRD ID
Ensembl ID		ENSG00000255009	ENSG00000214513
Uniprot IDs		P0CB47	A8MTQ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell Olfactory Receptor Activity Sensory Perception Of Smell Detection Of Chemical Stimulus Involved In Sensory Perception Detection Of Chemical Stimulus Sensory Perception Of Chemical Stimulus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Detection Of Stimulus Involved In Sensory Perception Dorsal/ventral Pattern Formation Neuron Differentiation DNA Binding	Intermediate Filament Positive Regulation Of Low-density Lipoprotein Particle Clearance Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Low-density Lipoprotein Particle Clearance
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