UBTFL1 and BEND3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBTFL1	BEND3
Description		upstream binding transcription factor like 1	BEN domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Heterochromatin Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity DNA Binding Protein Binding	RDNA Binding DNA Binding Protein Binding
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Blastocyst Growth Transcription By RNA Polymerase I Embryo Implantation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase I	Negative Regulation Of Transcription By RNA Polymerase II RDNA Heterochromatin Formation Chromatin Organization DNA Methylation-dependent Constitutive Heterochromatin Formation Protein Homooligomerization Positive Regulation Of ATP Metabolic Process
Pathways
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	Brain morphology (MOSTest) ( 32665545) Hip index ( 34021172) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 27863252) Neutrophil percentage of white cells ( 32888494) Parental longevity (combined parental age at death) ( 29227965) Postprandial triglyceride response to high fat diet meal ( 26256467) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Subcortical volume (MOSTest) ( 32665545) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969)
Interacting Genes		30 interacting genes: BEND3 C3orf36 CCDC136 CDR2 DDIT4L FSD2 GOLGA2 GOLGA6L9 LBX1 LDOC1 LHX2 LHX3 LHX9 MTUS2 NACC1 NOTO OR4F16 OR4F29 OR4F3 OR5AS1 PBX4 PUF60 RABEP1 RUNDC3A STX1A TAX1BP1 TFIP11 ZBTB7B ZCCHC9 ZNF558	5 interacting genes: DPY30 FAM161A MCRS1 MORN4 UBTFL1
Entrez ID		642623	57673
HPRD ID			18934
Ensembl ID		ENSG00000255009	ENSG00000178409
Uniprot IDs		P0CB47	Q5T5X7
PDB IDs			5JNO 7W27
Enriched GO Terms of Interacting Partners?		Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell Olfactory Receptor Activity Sensory Perception Of Smell Detection Of Chemical Stimulus Involved In Sensory Perception Detection Of Chemical Stimulus Sensory Perception Of Chemical Stimulus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Detection Of Stimulus Involved In Sensory Perception Dorsal/ventral Pattern Formation Neuron Differentiation DNA Binding	MLL1 Complex NSL Complex Poly(G) Binding Telomerase Inhibitor Activity Regulation Of DNA Strand Elongation Regulation Of Protein Localization To Nucleolus Positive Regulation Of Protein Localization To Nucleolus Ino80 Complex G-quadruplex RNA Binding Positive Regulation Of Telomere Maintenance In Response To DNA Damage Astral Microtubule Set1C/COMPASS Complex MLL1/2 Complex MLL3/4 Complex Stereocilium Tip Actin-based Cell Projection Transcription By RNA Polymerase I RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity Blastocyst Growth RNA Polymerase I Preinitiation Complex Assembly Filopodium Tip
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