UBTFL1 and RABEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		UBTFL1	RABEP1
Description		upstream binding transcription factor like 1	rabaptin, RAB GTPase binding effector protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Endosome Early Endosome Cytosol Endocytic Vesicle Cytoplasmic Vesicle Early Endosome Membrane Protein-containing Complex Recycling Endosome Glutamatergic Synapse
	Molecular Function	RNA Polymerase I Core Promoter Sequence-specific DNA Binding RNA Polymerase I General Transcription Initiation Factor Activity DNA Binding Protein Binding	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	RNA Polymerase I Preinitiation Complex Assembly Blastocyst Growth Transcription By RNA Polymerase I Embryo Implantation Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase I	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Membrane Fusion Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Protein Localization To Ciliary Membrane
Pathways			TBC/RABGAPs
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	Body mass index ( 25673413 28892062) Lymphocyte count ( 32888494) Mean platelet volume ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)
Interacting Genes		30 interacting genes: BEND3 C3orf36 CCDC136 CDR2 DDIT4L FSD2 GOLGA2 GOLGA6L9 LBX1 LDOC1 LHX2 LHX3 LHX9 MTUS2 NACC1 NOTO OR4F16 OR4F29 OR4F3 OR5AS1 PBX4 PUF60 RABEP1 RUNDC3A STX1A TAX1BP1 TFIP11 ZBTB7B ZCCHC9 ZNF558	60 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 NRIP1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNCA SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774
Entrez ID		642623	9135
HPRD ID			04684
Ensembl ID		ENSG00000255009	ENSG00000029725
Uniprot IDs		P0CB47	B4DMM4 Q15276
PDB IDs			1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?		Detection Of Chemical Stimulus Involved In Sensory Perception Of Smell Olfactory Receptor Activity Sensory Perception Of Smell Detection Of Chemical Stimulus Involved In Sensory Perception Detection Of Chemical Stimulus Sensory Perception Of Chemical Stimulus DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Detection Of Stimulus Involved In Sensory Perception Dorsal/ventral Pattern Formation Neuron Differentiation DNA Binding	Intracellular Protein Localization Vesicle-mediated Transport Golgi Vesicle Transport Protein Binding Early Endosome Membrane Protein Transport Establishment Of Protein Localization Endosome Intracellular Transport Regulation Of Vesicle-mediated Transport G Protein Activity Recycling Endosome Cellular Localization Establishment Of Localization In Cell Vesicle-mediated Transport In Synapse Intracellular Protein Transport Rab Protein Signal Transduction Post-Golgi Vesicle-mediated Transport Endosomal Transport Intracellular Vesicle Regulation Of Exocytosis Small GTPase Binding Positive Regulation Of Protein Metabolic Process Intracellular Signal Transduction GTPase Activity Early Endosome Post-translational Protein Modification Protein Localization To Cell Surface Presynapse Insulin-responsive Compartment Negative Regulation Of Exocytosis Golgi To Plasma Membrane Protein Transport Vacuolar Transport Synaptic Vesicle Endocytosis Cytoplasmic Vesicle Membrane Protein Localization To Organelle Nucleus Secretion Protein Modification Process Secretion By Cell Protein Polyubiquitination Presynaptic Endocytosis Regulation Of MRNA 3'-end Processing Endosome Membrane Protein Localization To Plasma Membrane Positive Regulation Of Translational Initiation Regulation Of Endosome Size Regulation Of Cellular Component Organization Exocytosis AP-1 Adaptor Complex
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