DNAJC1 and ABHD16A

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAJC1	ABHD16A
Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 1	abhydrolase domain containing 16A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Nuclear Membrane	Integral Component Of Membrane
	Molecular Function	ATPase Activator Activity DNA Binding Chromatin Binding Protein Binding Chaperone Binding	Hydrolase Activity
	Biological Process	Regulation Of Translation Protein Folding Positive Regulation Of ATPase Activity Negative Regulation Of Proteolysis Regulation Of Protein Secretion	Metabolic Process
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Ovarian cancer ( 23535730)
Protein-Protein Interactions		4 interactors: ABHD16A HSPA5 ITIH4 SERPINA3	19 interactors: ATP5G3 DNAJC1 DTX2 FAM134C GPRC5C HM13 HNRNPA1 IFITM1 MLH1 ND3 ND4 PILRB PTGS2 RNF5 SAFB SPAG7 TMEM147 TMEM222 UPF1
Entrez ID		64215	7920
HPRD ID		09922	15929
Ensembl ID		ENSG00000136770	ENSG00000204427
Uniprot IDs		Q96KC8	B3KNX9 O95870
PDB IDs		2CQQ 2CQR
Enriched GO Terms of Interacting Partners?		Acute-phase Response Acute Inflammatory Response Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity ER Overload Response Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Maintenance Of Protein Localization In Endoplasmic Reticulum Inflammatory Response Regulation Of Cellular Protein Metabolic Process Maintenance Of Gastrointestinal Epithelium Regulation Of Protein Metabolic Process Cellular Response To Antibiotic Epithelial Structure Maintenance Anatomical Structure Arrangement Regulation Of Catalytic Activity Cellular Response To Toxic Substance Cellular Response To Glucose Starvation Regulation Of Proteolysis Response To Cytokine Cerebellar Purkinje Cell Layer Development Negative Regulation Of Catalytic Activity Substantia Nigra Development Hyaluronan Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Toxin Transport Cellular Response To Interleukin-4 Negative Regulation Of Protein Metabolic Process Response To Interleukin-4 Cerebellum Morphogenesis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Neural Nucleus Development Hindbrain Morphogenesis Positive Regulation Of Nuclease Activity Response To Antibiotic Response To Stress Cerebellar Cortex Development Platelet Degranulation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway	Respiratory Electron Transport Chain Electron Transport Chain ATP Metabolic Process Cellular Respiration Mitochondrial Electron Transport, NADH To Ubiquinone Nucleotide Metabolic Process Purine Nucleoside Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Mitochondrial ATP Synthesis Coupled Electron Transport Maintenance Of Blood-brain Barrier Meiotic Metaphase I Plate Congression Meiotic Spindle Midzone Assembly Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Oxidative Phosphorylation RNA Export From Nucleus Negative Regulation Of Mitotic Recombination ER-associated Misfolded Protein Catabolic Process Positive Regulation Of Fibroblast Growth Factor Production Generation Of Precursor Metabolites And Energy Female Gamete Generation Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Negative Regulation Of Synaptic Transmission, Dopaminergic Nicotinamide Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Production Nuclear Export MRNA Transport Posttranscriptional Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Organophosphate Metabolic Process RNA Transport Positive Regulation Of Brown Fat Cell Differentiation Nuclear-transcribed MRNA Catabolic Process RNA Localization Heterocycle Metabolic Process MRNA Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Prostaglandin Biosynthetic Process MRNA Catabolic Process Positive Regulation Of Synaptic Plasticity Spindle Midzone Assembly Positive Regulation Of Sprouting Angiogenesis Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process
Tagcloud ?		10p12 af10 blasts bmi1 break calm centromeric comm commd3 enrichment gives homolog hsp40 immediately insertion leukemias leukemic lymphoblastic mlv mo p12 q14 recurring semiquantitative spag6 sperm striking subfamily transcriptase	15d abpp bat5 c14 c18 c20 c7600 dag delta12 diacylglycerol ebelactone genuine glycerolipid hbat5 j2 linoleylglycerol lysophospholipase mag mags monoacylglycerols oxadiazol palmostatin pave pgj2 phenoxyphenyl tetrahydrolipstatin triacylglycerol unveiling
Tagcloud (Difference) ?		10p12 af10 blasts bmi1 break calm centromeric comm commd3 enrichment gives homolog hsp40 immediately insertion leukemias leukemic lymphoblastic mlv mo p12 q14 recurring semiquantitative spag6 sperm striking subfamily transcriptase	15d abpp bat5 c14 c18 c20 c7600 dag delta12 diacylglycerol ebelactone genuine glycerolipid hbat5 j2 linoleylglycerol lysophospholipase mag mags monoacylglycerols oxadiazol palmostatin pave pgj2 phenoxyphenyl tetrahydrolipstatin triacylglycerol unveiling
Tagcloud (Intersection) ?