DNAJC1

Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 1
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	ATPase Activator Activity DNA Binding Chromatin Binding Protein Binding Chaperone Binding
	Biological Process	Regulation Of Translation Protein Folding Positive Regulation Of ATPase Activity Negative Regulation Of Proteolysis Regulation Of Protein Secretion
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Ovarian cancer ( 23535730)
Protein-protein Interactions		4 interactors: ABHD16A HSPA5 ITIH4 SERPINA3
Entrez ID		64215
HPRD ID		09922
Ensembl ID		ENSG00000136770
Uniprot IDs		Q96KC8
PDB IDs		2CQQ 2CQR
Enriched GO Terms of Interacting Partners?		Acute-phase Response Acute Inflammatory Response Regulation Of Protein Folding In Endoplasmic Reticulum Cerebellum Structural Organization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity ER Overload Response Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Maintenance Of Protein Localization In Endoplasmic Reticulum Inflammatory Response Regulation Of Cellular Protein Metabolic Process Maintenance Of Gastrointestinal Epithelium Regulation Of Protein Metabolic Process Cellular Response To Antibiotic Epithelial Structure Maintenance Anatomical Structure Arrangement Regulation Of Catalytic Activity Cellular Response To Toxic Substance Cellular Response To Glucose Starvation Regulation Of Proteolysis Response To Cytokine Cerebellar Purkinje Cell Layer Development Negative Regulation Of Catalytic Activity Substantia Nigra Development Hyaluronan Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cellular Protein Metabolic Process Toxin Transport Cellular Response To Interleukin-4 Negative Regulation Of Protein Metabolic Process Response To Interleukin-4 Cerebellum Morphogenesis Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Neural Nucleus Development Hindbrain Morphogenesis Positive Regulation Of Nuclease Activity Response To Antibiotic Response To Stress Cerebellar Cortex Development Platelet Degranulation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		10p12 af10 blasts bmi1 break calm centromeric comm commd3 enrichment gives homolog hsp40 immediately insertion leukemias leukemic lymphoblastic mlv mo p12 q14 recurring semiquantitative spag6 sperm striking subfamily transcriptase