DNAJC1

Description		DnaJ heat shock protein family (Hsp40) member C1
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GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Endomembrane System Membrane Nuclear Membrane
	Molecular Function	ATPase Activator Activity DNA Binding Protein Binding Protein-folding Chaperone Binding
	Biological Process	Regulation Of Translation Protein Folding Negative Regulation Of Proteolysis Regulation Of Protein Secretion Regulation Of Protein Metabolic Process
Pathways
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33339817) Benign prostatic hyperplasia and lower urinary tract symptoms ( 30410027) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 23535729 29059683) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Essential hypertension (time to event) ( 32589924) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Oily fish consumption ( 32066663) Ovarian cancer ( 23535730) Pork consumption ( 32066663) Raw vegetable consumption ( 32066663) Subcutaneous adipose tissue ( 26480920) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		12 interacting genes: ABHD16A AGTRAP ATP6V0C CFTR CMTM7 CYP4F2 HSPA5 ITIH4 PLP2 SERPINA3 TMEM201 TNFRSF10C
Entrez ID		64215
HPRD ID		09922
Ensembl ID		ENSG00000136770
Uniprot IDs		Q96KC8
PDB IDs		2CQQ 2CQR
Enriched GO Terms of Interacting Partners?		Multicellular Organismal-level Water Homeostasis Peptidase Inhibitor Activity Acute-phase Response Serine-type Endopeptidase Inhibitor Activity Acute Inflammatory Response Regulation Of Cellular PH Regulation Of PH Regulation Of Intracellular PH Membrane Protein-folding Chaperone Binding Endoplasmic Reticulum Endoplasmic Reticulum Membrane Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Multicellular Organismal-level Chemical Homeostasis Positive Regulation Of Monoatomic Anion Transport Cerebellum Structural Organization Regulation Of ATF6-mediated Unfolded Protein Response Regulation Of Protein Folding In Endoplasmic Reticulum Phosphatidylserine Catabolic Process Fatty Acid Derivative Metabolic Process Prostaglandin Catabolic Process Alpha-tocopherol Omega-hydroxylase Activity Negative Regulation Of Icosanoid Secretion Leukotriene B4 Catabolic Process 20-hydroxy-leukotriene B4 Omega Oxidase Activity Alkane 1-monooxygenase Activity 20-aldehyde-leukotriene B4 20-monooxygenase Activity Leukotriene B4 Metabolic Process Arachidonate Omega-hydroxylase Activity Leukotriene-B4 20-monooxygenase Activity Pressure Natriuresis Angiotensin Type II Receptor Activity B-1a B Cell Differentiation B-1 B Cell Differentiation Nuclear Migration Along Microtubule Blood Microparticle Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Transepithelial Water Transport Monoacylglycerol Catabolic Process Vitamin E Metabolic Process Menaquinone Catabolic Process TRAIL Binding Multicellular Organismal-level Homeostasis Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Positive Regulation Of Tooth Mineralization
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