SETMAR and H3F3C

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SETMAR	H3F3C
Gene Name		SET domain and mariner transposase fusion gene	H3 histone, family 3C
Image
Gene Ontology Annotations	Cellular Component	Condensed Chromosome Nucleus Site Of Double-strand Break	Nucleosome Nuclear Euchromatin
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity Double-stranded DNA Binding Single-stranded DNA Binding Endonuclease Activity Transposase Activity Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K4 Specific) Protein Homodimerization Activity Structure-specific DNA Binding DNA Topoisomerase Binding Histone Methyltransferase Activity (H3-K36 Specific)	Nucleosomal DNA Binding Protein Heterodimerization Activity
	Biological Process	DNA Double-strand Break Processing DNA Catabolic Process, Endonucleolytic Double-strand Break Repair Via Nonhomologous End Joining Transposition, DNA-mediated Cell Proliferation Histone H3-K36 Methylation DNA Integration Replication Fork Processing Mitotic DNA Integrity Checkpoint Histone H3-K4 Methylation Negative Regulation Of Cell Cycle Arrest Nucleic Acid Phosphodiester Bond Hydrolysis Histone H3-K36 Dimethylation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Chromosome Organization	Positive Regulation Of Cell Growth
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: H3F3C	12 interactors: KAT6A KDM1A KDM4B NASP PRMT5 PRMT6 PRMT7 SETMAR SMYD1 SMYD3 SUV39H1 WHSC1L1
Entrez ID		6419	440093
HPRD ID		10225	18443
Ensembl ID		ENSG00000170364	ENSG00000188375
Uniprot IDs		B4DY74 C9JHK2 E7EN68 Q53H47	Q6NXT2
PDB IDs		3BO5 3F2K 3K9J 3K9K	3KV4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Growth Positive Regulation Of Growth Regulation Of Cell Growth	Chromatin Modification Chromatin Organization Chromosome Organization Histone Modification Histone Methylation Protein Methylation Methylation Organelle Organization Peptidyl-amino Acid Modification Histone Lysine Methylation Peptidyl-lysine Methylation Peptidyl-lysine Modification Histone H4-R3 Methylation Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Cellular Protein Modification Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Cellular Macromolecular Complex Assembly Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Peptidyl-lysine Dimethylation Protein Metabolic Process Nucleosome Assembly Regulation Of Metabolic Process Chromatin Assembly
Tagcloud ?		arrests associates break chk1 concerted differentiates dsb dsbs effectors effort fails fork forks ionizing lend lys36 methylates metnase phosphorylating repair replication repressing restart s495 s495a ser495 ser495ala stalled transposase
Tagcloud (Difference) ?		arrests associates break chk1 concerted differentiates dsb dsbs effectors effort fails fork forks ionizing lend lys36 methylates metnase phosphorylating repair replication repressing restart s495 s495a ser495 ser495ala stalled transposase
Tagcloud (Intersection) ?