SETMAR and VPS26C

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		SETMAR	VPS26C
Description		SET and mariner transposase domain methyltransferase	VPS26 endosomal protein sorting factor C
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GO Annotations	Cellular Component	Condensed Chromosome Nucleus Chromosome Nucleolus Site Of Double-strand Break	Nucleus Endosome
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity Nucleic Acid Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Catalytic Activity Nuclease Activity Endonuclease Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Protein-lysine N-methyltransferase Activity Transferase Activity Hydrolase Activity Histone Methyltransferase Activity Histone H3K4 Methyltransferase Activity Protein Homodimerization Activity DNA Topoisomerase Binding Metal Ion Binding Histone H3K36 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K36 Dimethyltransferase Activity	Protein Binding
	Biological Process	DNA Double-strand Break Processing DNA Repair Double-strand Break Repair Via Nonhomologous End Joining DNA Catabolic Process Chromatin Organization Chromatin Remodeling DNA Damage Response Cell Population Proliferation DNA Integration Replication Fork Processing Methylation Mitotic DNA Integrity Checkpoint Signaling Nucleic Acid Metabolic Process Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Negative Regulation Of Chromosome Organization	Intracellular Protein Transport Endocytic Recycling
Pathways
Drugs
Diseases
GWAS		Fractures (paediatric) ( 32742401) Midgestational circulating levels of PCBs ( 28235828) Periodontitis (DPAL) ( 24024966) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Spondylosis ( 33332786)
Interacting Genes		3 interacting genes: H3-5 PRPF19 VPS26C	44 interacting genes: AGTPBP1 ARHGAP21 ASH1L CBLB CCDC85A CIPC DCLK1 DDIT4L DECR2 DNAJB2 EPHB6 INCA1 KIF1A KIF21A LRIF1 MAML3 MAPK6 MAPK8IP1 MDM4 MEI4 MEOX2 MRPS35 MYRIP NRCAM NSMF PALS2 PCM1 PEG10 PMS2 PRKD2 PTPN21 RAB39B RAP1GAP RAP1GAP2 SETMAR TAF1C TEPSIN TET2 TRAPPC1 U2AF1 VPS26A VPS35L XPA ZNF655
Entrez ID		6419	10311
HPRD ID		10225	10390
Ensembl ID		ENSG00000170364	ENSG00000157538
Uniprot IDs		B4DND2 Q53H47 Q96H41	A8MTY9 A8MY26 O14972
PDB IDs		3BO5 3F2K 3K9J 3K9K 7S03	8P0X 8SYN 8SYO 9AU7
Enriched GO Terms of Interacting Partners?
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