SAMSN1 and SAP30

Number of citations of the paper that reports this interaction (PMID 20478393)
3

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SAMSN1	SAP30
Gene Name		SAM domain, SH3 domain and nuclear localization signals 1	Sin3A-associated protein, 30kDa
Image
Gene Ontology Annotations	Cellular Component	Ruffle Nucleus Cytosol	Histone Deacetylase Complex Nucleoplasm
	Molecular Function	Phosphotyrosine Binding Poly(A) RNA Binding	DNA Binding Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Gene Expression Skeletal Muscle Cell Differentiation Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	27 interactors: ARID4A BRMS1 BRMS1L CIR1 HBP1 HDAC1 HDAC2 HIST1H2AL HIST2H2BE HIST3H3 HIST4H4 HTT ID3 ING1 LINC00152 MXD1 NCOR1 NCOR2 PCBD1 RBBP4 RBBP7 RBP1 SAMSN1 SAP30BP SIN3A YY1 ZNF395
Entrez ID		64092	8819
HPRD ID		06413	04540
Ensembl ID		ENSG00000155307	ENSG00000164105
Uniprot IDs		F8WAA1 Q9NSI8	O75446
PDB IDs		2KEA	2KDP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Signal Transduction Positive Regulation Of Transport Positive Regulation Of Organelle Organization Apoptotic Process Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Regulation Of Apoptotic Process Protein Targeting Membrane Organization Substantia Nigra Development Regulation Of Cell Death Intracellular Protein Transport Regulation Of Organelle Organization Regulation Of Signal Transduction Neural Nucleus Development Negative Regulation Of Protein Dephosphorylation Regulation Of Cellular Component Organization Regulation Of Signaling Negative Regulation Of Cellular Metabolic Process Glucocorticoid Receptor Signaling Pathway Midbrain Development Cellular Protein Localization Protein Transport Establishment Of Protein Localization Signal Transduction Intracellular Transport Signaling Cell Communication Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity System Development Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated	Chromosome Organization Negative Regulation Of Gene Expression Chromatin Organization Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Chromatin Modification Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Gene Expression Heterocycle Metabolic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Regulation Of Metabolic Process Histone Deacetylation Histone Modification Protein Deacetylation ATP-dependent Chromatin Remodeling Rhythmic Process Histone H3-K9 Modification Transcription From RNA Polymerase II Promoter Circadian Rhythm Chromatin Remodeling CENP-A Containing Nucleosome Assembly Histone Exchange DNA Replication-independent Nucleosome Assembly Homeostatic Process Nucleosome Assembly Cellular Metabolic Process Chromatin Assembly Establishment Of Sertoli Cell Barrier
Tagcloud ?		11q 13q 14q 15q 1q 21q 22q 2q 3q 4p 4q 9q acgh acsl1 atp8b4 bcl1 fbxl5 imbalances irf2bp2 ivns1abp jh lamp2 myeloma nampt picalm q13 q32 stk17b xq	affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose
Tagcloud (Difference) ?		11q 13q 14q 15q 1q 21q 22q 2q 3q 4p 4q 9q acgh acsl1 atp8b4 bcl1 fbxl5 imbalances irf2bp2 ivns1abp jh lamp2 myeloma nampt picalm q13 q32 stk17b xq	affects chip deacetylation detecting differential dual encoded enzyme hdac herpes hsv htrp inhibit interact kmb luciferase lysine msin3a promote real regulator repressor reveal significance simplex synergistically transfer viral whose
Tagcloud (Intersection) ?