SAMSN1 and PILRB

Number of citations of the paper that reports this interaction (PubMedID 15381729)
55

Data Source:
HPRD (in vitro)

		SAMSN1	PILRB
Description		SAM domain, SH3 domain and nuclear localization signals 1	paired immunoglobin like type 2 receptor beta
Image
GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Cytosol Cell Projection	Plasma Membrane Membrane
	Molecular Function	Phosphotyrosine Residue Binding RNA Binding	Protein Binding MHC Class I Protein Binding
	Biological Process	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation Regulation Of Intracellular Signal Transduction	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)	Advanced age-related macular degeneration ( 26691988) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hemoglobin ( 32888494) Monocyte count ( 32888494) Post bronchodilator FEV1 ( 26634245) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	6 interacting genes: ABHD16A BRCA1 LYN PTPN11 PTPN6 SAMSN1
Entrez ID		64092	29990
HPRD ID		06413	08382
Ensembl ID		ENSG00000155307	ENSG00000121716
Uniprot IDs		A0A2R8Y4K8 Q9NSI8 S6FRS6	Q9UKJ0
PDB IDs		6UZJ	4NFC 4NFD
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Domain Specific Binding Protein Sequestering Activity Transmembrane Transporter Binding Protein Targeting Regulation Of Nucleocytoplasmic Transport Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization Phosphoprotein Binding Extracellular Exosome Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Substantia Nigra Development Negative Regulation Of RNA Metabolic Process Nuclear Receptor-mediated Corticosteroid Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transport Positive Regulation Of Nucleocytoplasmic Transport Neural Nucleus Development Negative Regulation Of Monoatomic Ion Transmembrane Transport Intracellular Protein Localization Regulation Of Intracellular Transport Cadherin Binding Negative Regulation Of Monoatomic Ion Transport Melanosome Signal Transduction Negative Regulation Of Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Intracellular Transport Positive Regulation Of Protein Export From Nucleus Enzyme Binding Regulation Of Monoatomic Ion Transport Regulation Of Intracellular Protein Transport Negative Regulation Of Transport Focal Adhesion Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Identical Protein Binding Intracellular Signal Transduction Regulation Of Protein Export From Nucleus Negative Regulation Of Metabolic Process Negative Regulation Of Protein Localization Regulation Of Macromolecule Metabolic Process	Regulation Of Neutrophil Activation Negative Regulation Of Immune System Process Negative Regulation Of Lymphocyte Activation Negative Regulation Of Leukocyte Activation T Cell Costimulation Regulation Of Cell Adhesion Mediated By Integrin Phosphotyrosine Residue Binding Negative Regulation Of Cell Activation Regulation Of Cell Activation Myeloid Cell Differentiation Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Cycle Process Negative Regulation Of Neutrophil Activation Protein-containing Complex Regulation Of Cytokine Production Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Cell-cell Adhesion Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Phosphorylation-dependent Protein Binding Negative Regulation Of Leukocyte Proliferation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Immune Effector Process Negative Regulation Of B Cell Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Phosphatase Activity Inflammatory Response To Wounding Neutrophil Activation Involved In Immune Response Regulation Of Immune Response Cytokine-mediated Signaling Pathway Regulation Of Cell Cycle Phase Transition Regulation Of Innate Immune Response Myeloid Leukocyte Activation Regulation Of Intracellular Signal Transduction Regulation Of B Cell Activation Regulation Of Cell Cycle Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Mitotic Cell Cycle Signal Transduction In Response To DNA Damage Regulation Of Mast Cell Activation Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Leukocyte Activation Involved In Immune Response Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Cell Activation Involved In Immune Response Negative Regulation Of Multicellular Organismal Process Peptidyl-tyrosine Dephosphorylation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?