SAMSN1

Description		SAM domain, SH3 domain and nuclear localization signals 1
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GO Annotations	Cellular Component	Ruffle Nucleus Cytoplasm Cytosol Cell Projection
	Molecular Function	Phosphotyrosine Residue Binding RNA Binding
	Biological Process	Negative Regulation Of Adaptive Immune Response Negative Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of B Cell Activation Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes		10 interacting genes: FASLG NEDD4 PILRB SAP30 SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		64092
HPRD ID		06413
Ensembl ID		ENSG00000155307
Uniprot IDs		A0A2R8Y4K8 Q9NSI8 S6FRS6
PDB IDs		6UZJ
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Domain Specific Binding Protein Sequestering Activity Transmembrane Transporter Binding Protein Targeting Regulation Of Nucleocytoplasmic Transport Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization Phosphoprotein Binding Extracellular Exosome Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Substantia Nigra Development Negative Regulation Of RNA Metabolic Process Nuclear Receptor-mediated Corticosteroid Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transport Positive Regulation Of Nucleocytoplasmic Transport Neural Nucleus Development Negative Regulation Of Monoatomic Ion Transmembrane Transport Intracellular Protein Localization Regulation Of Intracellular Transport Cadherin Binding Negative Regulation Of Monoatomic Ion Transport Melanosome Signal Transduction Negative Regulation Of Transmembrane Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Intracellular Transport Positive Regulation Of Protein Export From Nucleus Enzyme Binding Regulation Of Monoatomic Ion Transport Regulation Of Intracellular Protein Transport Negative Regulation Of Transport Focal Adhesion Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Localization Identical Protein Binding Intracellular Signal Transduction Regulation Of Protein Export From Nucleus Negative Regulation Of Metabolic Process Negative Regulation Of Protein Localization Regulation Of Macromolecule Metabolic Process
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