SELE and GLG1

Number of citations of the paper that reports this interaction (PMID 11404363)
14

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		SELE	GLG1
Gene Name		selectin E	golgi glycoprotein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Caveola Coated Pit Integral Component Of Membrane Cortical Cytoskeleton Membrane Raft Perinuclear Region Of Cytoplasm	Golgi Membrane Golgi Apparatus Plasma Membrane Membrane Integral Component Of Membrane Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Sialic Acid Binding Phospholipase Binding Oligosaccharide Binding	Receptor Binding
	Biological Process	Positive Regulation Of Receptor Internalization Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Leukocyte Migration Inflammatory Response Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Activation Of Phospholipase C Activity Blood Coagulation Calcium-mediated Signaling Actin Filament-based Process Response To Lipopolysaccharide Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukocyte Migration Leukocyte Tethering Or Rolling Response To Interleukin-1	Blood Coagulation Negative Regulation Of Protein Processing Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Chondrocyte Differentiation Leukocyte Migration Bone Morphogenesis
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs		O-Sialic Acid
Diseases
GWAS			Breast cancer ( 18463975) Testicular germ cell tumor ( 23666239)
Protein-Protein Interactions		13 interactors: ACTN2 CD44 FLNA GLG1 LGALS3BP PLCG1 PTK2 PTPN11 PXN SELL SELPLG SERPING1 VCL	2 interactors: NFKB2 SELE
Entrez ID		6401	2734
HPRD ID		00566	02855
Ensembl ID		ENSG00000007908
Uniprot IDs		P16581	Q92896
PDB IDs		1ESL 1G1T 1KJA
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Response To Stress Movement Of Cell Or Subcellular Component Leukocyte Migration Cell Adhesion Platelet Activation Platelet Degranulation Cell Migration Cell Motility Cell Projection Organization Cell Activation Cell Morphogenesis Involved In Differentiation Response To Stimulus Locomotion Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell-matrix Adhesion Adherens Junction Assembly Positive Regulation Of Intracellular Signal Transduction Cell Junction Assembly Vesicle-mediated Transport Cell-substrate Adhesion Immune System Process Regulation Of Protein Metabolic Process Signal Complex Assembly Anatomical Structure Morphogenesis Cellular Response To Growth Factor Stimulus Cell Morphogenesis Response To Growth Factor Adherens Junction Organization Cell Projection Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Exocytosis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Signal Transduction Defense Response Integrin-mediated Signaling Pathway Innate Immune Response Protein Localization To Cell Surface Cell Projection Morphogenesis Regulation Of Signaling Cell Part Morphogenesis Positive Regulation Of Phosphorylation Regulation Of Immune Response Positive Regulation Of MAPK Cascade	Follicular Dendritic Cell Differentiation Inflammatory Response Response To Cytokine Germinal Center Formation Leukocyte Tethering Or Rolling Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Immune System Process Positive Regulation Of Receptor Internalization Cellular Extravasation Regulation Of Receptor Internalization Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Immune System Process Positive Regulation Of Receptor-mediated Endocytosis Defense Response NIK/NF-kappaB Signaling Spleen Development Activation Of Phospholipase C Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Positive Regulation Of Phospholipase C Activity I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Phospholipase Activity Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Response To Interleukin-1 Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Positive Regulation Of Leukocyte Migration Calcium-mediated Signaling Immune System Process Positive Regulation Of Endocytosis Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Regulation Of Leukocyte Migration Positive Regulation Of NF-kappaB Transcription Factor Activity Response To Tumor Necrosis Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Response To Organic Substance Second-messenger-mediated Signaling Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		2000bp 500bp annotated cor cst11 cyp2b13 cyp2b9 cyp2d9 cyp3a41 cyp3a44 cyp4a10 cyp7b1 ddc defb43 esr2 fmo3 hsd3b5 hypo masculinization masculinize methylatable nimblegen permanently slco1a1 sult2a2 tss ugt2b1 ugt2b38 unmethylated	apoe apolipoprotein atherosclerosis atherosclerotic backcrossing c57bl6 carrying cgr deficiency e10 embryonic esl fewer fibroblast generations glycoprotein golgi heterozygous homocysteine intercrossed latent lethality ltcp multifunctional plaque selectin transforming viable widespread
Tagcloud (Difference) ?		2000bp 500bp annotated cor cst11 cyp2b13 cyp2b9 cyp2d9 cyp3a41 cyp3a44 cyp4a10 cyp7b1 ddc defb43 esr2 fmo3 hsd3b5 hypo masculinization masculinize methylatable nimblegen permanently slco1a1 sult2a2 tss ugt2b1 ugt2b38 unmethylated	apoe apolipoprotein atherosclerosis atherosclerotic backcrossing c57bl6 carrying cgr deficiency e10 embryonic esl fewer fibroblast generations glycoprotein golgi heterozygous homocysteine intercrossed latent lethality ltcp multifunctional plaque selectin transforming viable widespread
Tagcloud (Intersection) ?