SELE and GLG1

Number of citations: 0 (PubMedID 11404363)
Data Source: BioGRID (pull down), HPRD (in vitro, in vivo)

		SELE	GLG1
Name		selectin E	golgi glycoprotein 1
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Caveola Clathrin-coated Pit External Side Of Plasma Membrane Membrane Cortical Cytoskeleton Membrane Raft Perinuclear Region Of Cytoplasm	Golgi Membrane Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Sialic Acid Binding Phospholipase Binding Metal Ion Binding Oligosaccharide Binding	Signaling Receptor Binding Fibroblast Growth Factor Binding
	Biological Process	Positive Regulation Of Receptor Internalization Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Leukocyte Migration Inflammatory Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Calcium-mediated Signaling Actin Filament-based Process Response To Lipopolysaccharide Response To Cytokine Response To Tumor Necrosis Factor Regulation Of Inflammatory Response Leukocyte Migration Leukocyte Tethering Or Rolling Response To Interleukin-1 Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Leukocyte Tethering Or Rolling	Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Protein Processing Protein Processing Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Chondrocyte Differentiation Bone Morphogenesis
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs		Carvedilol N-acetyl-alpha-neuraminic acid Endostatin	None
GWAS		Blood protein levels ( 30072576 ) Inflammatory bowel disease ( 26192919 ) Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 32888494 )	Basophil count ( 32888494 ) Breast cancer ( 18463975 ) General risk tolerance (MTAG) ( 30643258 ) Granulocyte percentage of myeloid white cells ( 27863252 ) Monocyte count ( 32888494 ) Monocyte percentage of white cells ( 27863252 32888494 ) Neutrophil count ( 32888494 ) Neutrophil percentage of white cells ( 27863252 32888494 ) Plasma anti-thyroid peroxidase levels ( 29678681 ) Testicular germ cell tumor ( 23666239 ) White blood cell count ( 32888494 )
Interacting Genes		16 interacting genes: ACTA2 ACTN2 CD44 FLNA GLG1 LGALS3BP PLCG1 PTK2 PTPN11 PXN SELL SELPLG SERPING1 SNCA TRIM54 VCL	6 interacting genes: GOLPH3 GOLPH3L MTDH NFKB2 SELE UBC
Entrez ID		6401	2734
HPRD ID		00566	02855
Ensembl ID		ENSG00000007908	ENSG00000090863
Uniprot IDs		P16581	Q92896
PDB IDs		1ESL 1G1T 4C16 4CSY 6EYI 6EYJ 6EYK 8R5L 8R5M	Not available
GO Terms Enriched among Interactors		Cell Adhesion Cell Migration Cytoskeleton Focal Adhesion Cell Motility Cellular Response To Growth Factor Stimulus Actin Cytoskeleton Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Cytoskeleton Organization Response To Growth Factor Actin Binding Regulation Of Supramolecular Fiber Organization Leukocyte Cell-cell Adhesion Cell Cortex Positive Regulation Of Monoatomic Ion Transport Signal Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Stress Fiber Cell Projection Cell-cell Adhesion Regulation Of Monoatomic Cation Transmembrane Transport Positive Regulation Of Fibroblast Migration Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cellular Component Organization Immune System Process Regulation Of Monoatomic Ion Transmembrane Transport Leukocyte Tethering Or Rolling Megakaryocyte Development Leukocyte Adhesion To Vascular Endothelial Cell Extracellular Exosome Regulation Of Metal Ion Transport Z Disc Regulation Of Sequestering Of Calcium Ion Enzyme-linked Receptor Protein Signaling Pathway Growth Hormone Receptor Signaling Pathway Regulation Of Locomotion Wound Healing, Spreading Of Cells Regulation Of Actin Filament-based Process Cellular Response To Fibroblast Growth Factor Stimulus Protein Localization To Cell Surface Cell-substrate Adhesion Regulation Of Multicellular Organismal Process Protein-containing Complex Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Potassium Ion Transport Regulation Of Organelle Organization Plasma Membrane Regulation Of Monoatomic Ion Transport	Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Leukocyte Tethering Or Rolling Leukocyte Adhesion To Vascular Endothelial Cell Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Leukocyte Cell-cell Adhesion Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Bcl3/NF-kappaB2 Complex Follicular Dendritic Cell Differentiation Golgi Organization Asymmetric Golgi Ribbon Formation I-kappaB/NF-kappaB Complex Follicular Dendritic Cell Activation Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Retention In Golgi Apparatus Trans-Golgi Network Protein Localization To Plasma Membrane Positive Regulation Of Transport Protein Targeting Establishment Of Protein Localization To Membrane Response To Rapamycin Intercellular Canaliculus Protein Localization To Cell Periphery Positive Regulation Of Protein Transport Germinal Center Formation Positive Regulation Of Leukocyte Tethering Or Rolling Regulation Of Protein Secretion Golgi Ribbon Formation Golgi Vesicle Transport Cellular Response To Ether Response To Lipopolysaccharide Oligosaccharide Binding Positive Regulation Of Secretion By Cell Protein Localization To Membrane Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Response To Molecule Of Bacterial Origin Regulation Of Leukocyte Tethering Or Rolling