BAP1

Gene Name		BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm PR-DUB Complex
	Molecular Function	Chromatin Binding Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity
	Biological Process	Regulation Of Cell Growth Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Proliferation Protein Deubiquitination Monoubiquitinated Protein Deubiquitination Monoubiquitinated Histone H2A Deubiquitination Regulation Of Cell Cycle Protein K48-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		10 interactors: BRCA1 HIST2H2AA3 HIST2H2AC TRIM63 UBE2O USP15 USP2 USP21 USP28 YY1
Entrez ID		8314
HPRD ID		04366
Ensembl ID		ENSG00000163930
Uniprot IDs		Q92560
PDB IDs
Enriched GO Terms of Interacting Partners?		Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Deubiquitination Protein Modification By Small Protein Removal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Response To Radiation Histone Deubiquitination Response To Abiotic Stimulus Cellular Protein Modification Process Regulation Of Proteolysis Proteolysis Cellular Response To UV Response To Light Stimulus Catabolic Process Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Cellular Protein Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Regulation Of Cellular Protein Metabolic Process Cellular Response To Light Stimulus Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Histone H3-K9 Acetylation Histone H2B Conserved C-terminal Lysine Deubiquitination Response To Prostaglandin F Signal Transduction By P53 Class Mediator Regulation Of Protein Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Response To UV Protein Ubiquitination Cellular Response To Radiation DNA Repair Response To Ionizing Radiation Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Protein Modification By Small Protein Conjugation Double-strand Break Repair DNA Damage Checkpoint Cellular Response To Indole-3-methanol Protein Metabolic Process Protein Polyubiquitination Negative Regulation Of Centriole Replication Skeletal Muscle Atrophy
Tagcloud ?		1000x abstracted arid1a cca cdkn2a cholangiocarcinoma entities extrahepatic fbxw7 fgfr gas hiseq hotspot idh1 illumina indolent intrahepatic introns kras mcl1 ngs pbrm1 pgm presentations radiologic sequencer smad4 targetable worse