PF4V1 and XCL2

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		PF4V1	XCL2
Description		platelet factor 4 variant 1	X-C motif chemokine ligand 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide	Chemotaxis Inflammatory Response Immune Response Signal Transduction Blood Circulation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall	Chemokine receptors bind chemokines G alpha (q) signalling events
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Emphysema imaging phenotypes ( 26030696) Lung cancer ( 28604730) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2	19 interacting genes: CCL2 CCL20 CCL21 CCL26 CCL28 CCL5 CCL7 CCL8 CXCL12 CXCL17 CXCL2 CXCL3 CXCL5 KRTAP1-3 KRTAP10-9 NOTCH2NLA PF4 PF4V1 XCR1
Entrez ID		5197	6846
HPRD ID		01427	05317
Ensembl ID		ENSG00000109272	ENSG00000143185
Uniprot IDs		P10720	Q9UBD3
PDB IDs		4HSV
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemotaxis Locomotion Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration CCR Chemokine Receptor Binding Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemokine Receptor Binding Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Cell Motility Response To Other Organism Immune Response Eosinophil Chemotaxis Eosinophil Migration Response To External Biotic Stimulus Defense Response Extracellular Space G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Mononuclear Cell Migration Regulation Of Locomotion Extracellular Region Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Lymphocyte Migration Regulation Of Leukocyte Migration Response To Stress Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Extravasation Cell Surface Receptor Signaling Pathway	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Antimicrobial Humoral Response Locomotion Leukocyte Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Granulocyte Chemotaxis Myeloid Leukocyte Migration Granulocyte Migration Cell Migration Inflammatory Response Cell Motility Defense Response To Symbiont Defense Response To Other Organism Mononuclear Cell Migration Immune Response Chemokine-mediated Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Defense Response Response To Other Organism CCR Chemokine Receptor Binding Immune System Process Extracellular Space Killing Of Cells Of Another Organism Regulation Of Leukocyte Migration CXCR Chemokine Receptor Binding Extracellular Region Response To External Biotic Stimulus Positive Regulation Of Leukocyte Migration Positive Regulation Of Mononuclear Cell Migration Cell Killing Monocyte Chemotaxis Regulation Of Lymphocyte Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cytokine-mediated Signaling Pathway Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Lymphocyte Migration Regulation Of Chemotaxis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Positive Regulation Of Cell Motility Negative Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Locomotion
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