PF4V1 and CCL4L1

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		PF4V1	CCL4L1
Description		platelet factor 4 variant 1	C-C motif chemokine ligand 4 like 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Cellular Response To Lipopolysaccharide	Chemotaxis Inflammatory Response Immune Response Positive Regulation Of Cell Migration Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling G alpha (i) signalling events
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)	Body mass index ( 26426971) Macrophage inflammatory protein 1b levels ( 27989323)
Interacting Genes		15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2	3 interacting genes: CCL2 CXCL13 PF4V1
Entrez ID		5197	388372
HPRD ID		01427	16689
Ensembl ID		ENSG00000109272
Uniprot IDs		P10720	P13236 Q8NHW4
PDB IDs		4HSV	1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?		Chemokine Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemotaxis Locomotion Leukocyte Migration Granulocyte Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration CCR Chemokine Receptor Binding Cell Killing Defense Response To Symbiont Defense Response To Other Organism Chemokine Receptor Binding Inflammatory Response Cell Migration Cytokine-mediated Signaling Pathway Cell Motility Response To Other Organism Immune Response Eosinophil Chemotaxis Eosinophil Migration Response To External Biotic Stimulus Defense Response Extracellular Space G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Immune System Process Regulation Of Cell Migration Regulation Of Cell Motility Mononuclear Cell Migration Regulation Of Locomotion Extracellular Region Lymphocyte Chemotaxis CXCR Chemokine Receptor Binding Negative Regulation Of Leukocyte Tethering Or Rolling Lymphocyte Migration Regulation Of Leukocyte Migration Response To Stress Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Extravasation Cell Surface Receptor Signaling Pathway	Chemokine Activity Granulocyte Chemotaxis Granulocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Leukocyte Chemotaxis Antimicrobial Humoral Response Cellular Response To Lipopolysaccharide CXCR Chemokine Receptor Binding Cell Chemotaxis Cellular Response To Molecule Of Bacterial Origin Cytokine Activity Leukocyte Migration Humoral Immune Response Response To Lipopolysaccharide Regulation Of Lymphocyte Chemotaxis Response To Molecule Of Bacterial Origin Chemotaxis Locomotion Cellular Response To Lipid Negative Regulation Of Chemotaxis Neutrophil Chemotaxis Lymphocyte Migration Inflammatory Response Neutrophil Migration Regulation Of Lymphocyte Migration Chemokine-mediated Signaling Pathway Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Response To Lipid Mononuclear Cell Migration Cellular Response To Oxygen-containing Compound Cell Migration Helper T Cell Extravasation Chemokine (C-C Motif) Ligand 2 Signaling Pathway CXCR5 Chemokine Receptor Binding Lymphocyte Chemotaxis Across High Endothelial Venule Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Cell Motility Positive Regulation Of Leukocyte Migration Heparin Binding Response To Other Organism Immune Response Negative Regulation Of Natural Killer Cell Chemotaxis Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Response To External Biotic Stimulus
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