CCL18 and CRMP1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCL18	CRMP1
Gene Name		chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	collapsin response mediator protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Cytoplasm Microtubule Organizing Center Spindle Cytosol Dendrite Neuronal Cell Body
	Molecular Function	Protein Binding Chemokine Activity	Protein Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Cyclic Amides
	Biological Process	Chemotaxis Inflammatory Response Immune Response Cell Communication Signal Transduction Cell-cell Signaling Response To Biotic Stimulus Cell Chemotaxis	Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance
Pathways			Axon guidance Semaphorin interactions CRMPs in Sema3A signaling
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494)
Protein-Protein Interactions		6 interactors: C14orf1 CRMP1 EEF1A1 TLE1 TP53 UNC119	78 interactors: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LSM2 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1D1 ZAK ZNF24
Entrez ID		6362	1400
HPRD ID		04784	03913
Ensembl ID			ENSG00000072832
Uniprot IDs		P55774	B3KT07 E9PD68 Q14194 Q96I11
PDB IDs			4B3Z
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Macromitophagy Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Notch Signaling Pathway Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Regulation Of Caveolin-mediated Endocytosis Mitochondrial DNA Repair Mitotic Cytokinetic Process Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Pyrimidine Nucleobase Catabolic Process Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Response To Light Stimulus Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Anoikis Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Thymocyte Apoptotic Process Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior Regulation Of Anoikis Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Cell Separation After Cytokinesis Rhythmic Behavior Lipoprotein Transport Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Protein Oligomerization Negative Regulation Of Receptor-mediated Endocytosis Response To Radiation	Cell Death Death Developmental Process Apoptotic Process Programmed Cell Death Anatomical Structure Development Regulation Of Cellular Protein Metabolic Process Cell Differentiation Catabolic Process Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Cellular Response To Stress Regulation Of Cell Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Proteolysis Regulation Of Cysteine-type Endopeptidase Activity Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cellular Protein Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Organic Substance Protein Homooligomerization Response To Stress Protein Polyubiquitination Positive Regulation Of Protein Complex Assembly Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Nitrogen Compound Metabolic Process Cellular Response To Stimulus Multicellular Organismal Development Cytoskeleton Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Proteolysis Cellular Process Stress-activated MAPK Cascade Nervous System Development Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Cysteine-type Endopeptidase Activity System Development Positive Regulation Of Catalytic Activity Postreplication Repair Regulation Of Cellular Component Organization Protein Oligomerization Cellular Macromolecule Catabolic Process Positive Regulation Of Endopeptidase Activity Regulation Of Protein Complex Assembly Heterocycle Metabolic Process
Tagcloud ?		a0 aaa adventitia adventitial ageing aneurysm aortic collagens destabilization differentially distant fdg fluorodeoxyglucose layers medial metabolically metalloproteinases neg osteochondral paired pet pos positron prefacing rupture spot transcriptomic wall weakening	aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		a0 aaa adventitia adventitial ageing aneurysm aortic collagens destabilization differentially distant fdg fluorodeoxyglucose layers medial metabolically metalloproteinases neg osteochondral paired pet pos positron prefacing rupture spot transcriptomic wall weakening	aldh1a1 anxa1 bcar1 cldn1 endpoint folr1 foxm1 il12rb2 il7r inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?