CCL18 and CCL11

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL18	CCL11
Description		C-C motif chemokine ligand 18	C-C motif chemokine ligand 11
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding Protein Dimerization Activity Receptor Ligand Activity CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Cell Communication Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Positive Regulation Of Endothelial Cell Proliferation Chronic Inflammatory Response Mast Cell Chemotaxis Protein Phosphorylation Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Actin Filament Organization Cell Adhesion Signal Transduction Learning Or Memory Regulation Of Cell Shape Response To Radiation Response To Virus Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Killing Of Cells Of Another Organism Response To Interleukin-13 Positive Regulation Of Angiogenesis Eosinophil Chemotaxis Negative Regulation Of Neurogenesis Branching Involved In Mammary Gland Duct Morphogenesis Mammary Duct Terminal End Bud Growth Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway ERK1 And ERK2 Cascade Response To Interleukin-4
Pathways			Chemokine receptors bind chemokines Interleukin-4 and Interleukin-13 signaling
Drugs			CAT-213
Diseases
GWAS		Blood protein levels ( 30072576)	Crohn's disease ( 22412388 28067908) Gut microbiota (functional units) ( 27694959) Inflammatory bowel disease ( 23128233 28067908) Triglyceride levels in HIV infection ( 33109212)
Interacting Genes		7 interacting genes: CCL11 CRMP1 EEF1A1 ERG28 TLE1 TP53 UNC119	29 interacting genes: ACKR2 ACKR4 CCL13 CCL14 CCL18 CCL2 CCL26 CCL27 CCL28 CCL5 CCL8 CCR3 CCR5 CXCL1 CXCL10 CXCL11 CXCL12 CXCL14 CXCL2 CXCL3 CXCL5 CXCL6 CXCL9 DPP4 NUDT3 PF4 PF4V1 TPI1 XCL1
Entrez ID		6362	6356
HPRD ID		04784	03098
Ensembl ID		ENSG00000275385	ENSG00000172156
Uniprot IDs		P55774	P51671 Q6I9T4
PDB IDs		4MHE	1EOT 2EOT 2MPM 7SCS
Enriched GO Terms of Interacting Partners?		Centrosome Eukaryotic Translation Elongation Factor 1 Complex Negative Regulation Of Nervous System Development Mammary Duct Terminal End Bud Growth Response To Interleukin-13 Mast Cell Chemotaxis Response To Radiation CCR3 Chemokine Receptor Binding Negative Regulation Of Neurogenesis Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Histone Deacetylase Regulator Activity Negative Regulation Of Pentose-phosphate Shunt Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Response To Actinomycin D T Cell Proliferation Involved In Immune Response Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Negative Regulation Of G1 To G0 Transition Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Glial Cell Apoptotic Process Cellular Response To UV-C Germ Cell Nucleus Cellular Response To Actinomycin D ATP-dependent DNA/DNA Annealing Activity Negative Regulation Of Caveolin-mediated Endocytosis Negative Regulation Of Clathrin-dependent Endocytosis	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cytokine Activity Humoral Immune Response Chemokine-mediated Signaling Pathway Cell Migration Leukocyte Chemotaxis Cell Motility Inflammatory Response Granulocyte Chemotaxis Granulocyte Migration Immune Response Leukocyte Migration Defense Response Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Defense Response To Symbiont Defense Response To Other Organism Immune System Process CXCR Chemokine Receptor Binding Cytokine-mediated Signaling Pathway Cell Killing Response To External Biotic Stimulus Response To Other Organism Extracellular Space G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Neutrophil Migration CCR Chemokine Receptor Binding Response To Stress Extracellular Region Cell-cell Signaling Signaling Cell Communication Mononuclear Cell Migration Cellular Response To Lipopolysaccharide Signal Transduction Cellular Response To Molecule Of Bacterial Origin Chemokine Receptor Binding Response To Molecule Of Bacterial Origin CXCR3 Chemokine Receptor Binding Response To Lipopolysaccharide Cell Surface Receptor Signaling Pathway Eosinophil Chemotaxis Eosinophil Migration Positive Regulation Of Calcium Ion Transport
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