BICD1 and DYNC1I1

Number of citations of the paper that reports this interaction (PMID 17139249)
25

Data Source:
HPRD (in vivo)

		BICD1	DYNC1I1
Gene Name		bicaudal D homolog 1 (Drosophila)	dynein, cytoplasmic 1, intermediate chain 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Cytoplasmic Microtubule Membrane Cytoplasmic Vesicle Tubulin Complex Perinuclear Region Of Cytoplasm Host Cell Viral Assembly Compartment	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Rab GTPase Binding Proteinase Activated Receptor Binding Dynactin Binding Dynein Binding	Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding
	Biological Process	RNA Processing Intracellular MRNA Localization Anatomical Structure Morphogenesis Viral Process Protein Localization To Organelle Stress Granule Assembly Positive Regulation Of Receptor-mediated Endocytosis Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Phospholipase C Activity Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway	Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Vesicle Transport Along Microtubule
Pathways			MHC class II antigen presentation Adaptive Immune System
Drugs
Diseases
GWAS		Emphysema-related traits ( 20709820) Normalized brain volume ( 19010793) Obesity-related traits ( 23251661) Pancreatic cancer ( 20686608)	Immune reponse to smallpox (secreted IL-10) ( 22610502) Obesity-related traits ( 23251661)
Protein-Protein Interactions		12 interactors: ALPI CPNE4 DCTN1 DCTN2 DISC1 DYNC1I1 GSK3A GSK3B MAPK14 NIN RAB6A STAT3	31 interactors: ANXA7 BICD1 C2orf44 CADM4 CDKN1A DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 MCC NAGK NUDT21 PIN1 RAP1GAP RCC1 RUNDC3B SMN1 STAU1 TAOK1 TK1 TRIM58 UBC
Entrez ID		636	1780
HPRD ID		03730	04798
Ensembl ID		ENSG00000151746	ENSG00000158560
Uniprot IDs		A8MVZ6 Q96G01	A4D1I7 B4DME3 F5H050 G5E9K1 O14576 Q8N542 Q8TBF7
PDB IDs
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Negative Regulation Of Type B Pancreatic Cell Development Microtubule-based Process Hypermethylation Of CpG Island Cellular Localization Cellular Response To Interleukin-3 Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Generation Of Precursor Metabolites And Energy Antigen Processing And Presentation Regulation Of Wnt Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Immune System Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II ER-nucleus Signaling Pathway Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Peptidyl-threonine Phosphorylation Microtubule-based Transport Organelle Localization Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Protein Modification Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of DNA Methylation Regulation Of Carbohydrate Metabolic Process Response To Endoplasmic Reticulum Stress Intracellular Signal Transduction Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cardiac Muscle Hypertrophy Response To Lithium Ion Negative Regulation Of Wnt Signaling Pathway Establishment Of Vesicle Localization Melanosome Transport Regulation Of Glycogen Biosynthetic Process Pigment Granule Transport Cellular Response To Growth Factor Stimulus Vesicle Localization Establishment Of Melanosome Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Establishment Of Localization In Cell Response To Growth Factor Genetic Imprinting Negative Regulation Of Epithelial Cell Differentiation	Regulation Of Cellular Component Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Mitotic Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Signaling Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Regulation Of Catalytic Activity Positive Regulation Of Programmed Cell Death Intracellular MRNA Localization Positive Regulation Of Cell Death Regulation Of Organelle Organization Regulation Of Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Stress Granule Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Regulation Of Mitochondrion Organization Regulation Of Small GTPase Mediated Signal Transduction Microtubule-based Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Protein Tetramerization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Antigen Processing And Presentation Regulation Of Ras GTPase Activity Viral Process Mitotic Nuclear Division Intracellular Transport Of Virus Response To Metal Ion Positive Regulation Of Apoptotic Process Regulation Of Cell Growth Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Intracellular Signal Transduction DNA Damage Checkpoint Apoptotic Process G1/S Transition Of Mitotic Cell Cycle Fibroblast Growth Factor Receptor Signaling Pathway Programmed Cell Death Ribonucleoprotein Complex Assembly Negative Regulation Of Phosphorylation
Tagcloud ?			10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Difference) ?			10q24 17p13 cgh cnvs congenital deletions dlx5 duplications eexons encompassing enhancer enhancers exonic exons families foot fourth hearing hs1642 kb malformation microdeletions shfm shfm1 split syndromic telomeric tp63 unrelated
Tagcloud (Intersection) ?