BICD1 and CPNE4

Number of citations of the paper that reports this interaction (PMID 12522145)
20

Data Source:
HPRD (two hybrid, in vitro)

		BICD1	CPNE4
Gene Name		bicaudal D homolog 1 (Drosophila)	copine IV
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Cytoplasmic Microtubule Membrane Cytoplasmic Vesicle Tubulin Complex Perinuclear Region Of Cytoplasm Host Cell Viral Assembly Compartment	Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Cytoskeletal Adaptor Activity Rab GTPase Binding Proteinase Activated Receptor Binding Dynactin Binding Dynein Binding
	Biological Process	RNA Processing Intracellular MRNA Localization Anatomical Structure Morphogenesis Viral Process Protein Localization To Organelle Stress Granule Assembly Positive Regulation Of Receptor-mediated Endocytosis Minus-end-directed Organelle Transport Along Microtubule Microtubule Anchoring At Microtubule Organizing Center Negative Regulation Of Phospholipase C Activity Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Emphysema-related traits ( 20709820) Normalized brain volume ( 19010793) Obesity-related traits ( 23251661) Pancreatic cancer ( 20686608)	Amyotrophic lateral sclerosis ( 22959728) Neutrophil count ( 21507922)
Protein-Protein Interactions		12 interactors: ALPI CPNE4 DCTN1 DCTN2 DISC1 DYNC1I1 GSK3A GSK3B MAPK14 NIN RAB6A STAT3	16 interactors: ACTB BCOR BICD1 CCDC22 CEP162 CPNE1 MAP2K1 MYCBP PDCD6 PITPNM2 PPP5C RDX SKIL SPTBN1 UBE2M UBE2O
Entrez ID		636	131034
HPRD ID		03730	05017
Ensembl ID		ENSG00000151746	ENSG00000196353
Uniprot IDs		A8MVZ6 Q96G01	Q96A23
PDB IDs
Enriched GO Terms of Interacting Partners?		Movement Of Cell Or Subcellular Component Negative Regulation Of Type B Pancreatic Cell Development Microtubule-based Process Hypermethylation Of CpG Island Cellular Localization Cellular Response To Interleukin-3 Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Generation Of Precursor Metabolites And Energy Antigen Processing And Presentation Regulation Of Wnt Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Muscle Hypertrophy Regulation Of Glycogen (starch) Synthase Activity Immune System Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II ER-nucleus Signaling Pathway Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Peptidyl-threonine Phosphorylation Microtubule-based Transport Organelle Localization Cytoskeleton-dependent Intracellular Transport Positive Regulation Of Protein Modification Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of DNA Methylation Regulation Of Carbohydrate Metabolic Process Response To Endoplasmic Reticulum Stress Intracellular Signal Transduction Regulation Of Gene Expression By Genetic Imprinting Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cardiac Muscle Hypertrophy Response To Lithium Ion Negative Regulation Of Wnt Signaling Pathway Establishment Of Vesicle Localization Melanosome Transport Regulation Of Glycogen Biosynthetic Process Pigment Granule Transport Cellular Response To Growth Factor Stimulus Vesicle Localization Establishment Of Melanosome Localization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Establishment Of Localization In Cell Response To Growth Factor Genetic Imprinting Negative Regulation Of Epithelial Cell Differentiation	Cellular Component Assembly Enzyme Linked Receptor Protein Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Anatomical Structure Morphogenesis Protein Heterooligomerization Golgi To Plasma Membrane Transport Intracellular Transport Protein Monoubiquitination Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Actin Filament Capping Organelle Transport Along Microtubule Cell Projection Organization Regulation Of Proteinase Activated Receptor Activity Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Actin Filament Depolymerization Positive Regulation Of Signal Transduction Regulation Of Cellular Component Organization Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Regulation Of Signal Transduction Establishment Of Localization In Cell Negative Regulation Of Tooth Mineralization Negative Regulation Of Phospholipase C Activity Negative Regulation Of Protein Polymerization Post-Golgi Vesicle-mediated Transport Positive Regulation Of Intracellular Signal Transduction Anatomical Structure Development Negative Regulation Of Protein Complex Disassembly Transport Cell Projection Morphogenesis Vesicle-mediated Transport Minus-end-directed Organelle Transport Along Microtubule Axon Guidance Cell Part Morphogenesis Regulation Of Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Protein Depolymerization Regulation Of Organelle Organization Regulation Of Golgi Inheritance Protein Oligomerization Regulation Of Protein Complex Disassembly Specification Of Axis Polarity Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway Cellular Localization Negative Regulation Of Protein Complex Assembly Microtubule-based Transport Regulation Of Vascular Smooth Muscle Contraction Common-partner SMAD Protein Phosphorylation Negative Regulation Of Odontogenesis
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