CCL13 and CXCL10

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down, pull down)

		CCL13	CXCL10
Description		C-C motif chemokine ligand 13	C-X-C motif chemokine ligand 10
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space External Side Of Plasma Membrane
	Molecular Function	Signaling Receptor Binding Cytokine Activity Protein Binding Chemokine Activity CCR Chemokine Receptor Binding	Signaling Receptor Binding Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CAMP-dependent Protein Kinase Regulator Activity Chemoattractant Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway	Positive Regulation Of Leukocyte Chemotaxis Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Muscle Organ Development Blood Circulation Positive Regulation Of Cell Population Proliferation Response To Bacterium Response To Gamma Radiation T Cell Chemotaxis Regulation Of T Cell Chemotaxis Response To Auditory Stimulus Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Neutrophil Chemotaxis Killing Of Cells Of Another Organism Response To Lipopolysaccharide Response To Vitamin D Cellular Response To Heat Endothelial Cell Activation Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Positive Chemotaxis Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Monocyte Chemotaxis Cellular Response To Interleukin-17 Cellular Response To Virus Antiviral Innate Immune Response Regulation Of Endothelial Tube Morphogenesis Negative Regulation Of Myoblast Fusion Positive Regulation Of T Cell Migration
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs			N-Methylleucine Eldelumab Clove oil
Diseases
GWAS		Crohn's disease ( 22412388) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483)	Blood protein levels ( 30072576) C-X-C motif chemokine 10 levels ( 25147954) Hippocampal volume ( 29274321) Interferon gamma-induced protein 10 levels ( 27989323 31217265) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		26 interacting genes: ACKR2 ACKR4 APP CCL11 CCL2 CCL21 CCL24 CCL26 CCL28 CCL5 CCL8 CCR3 CCR5 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL9 HNRNPH3 MMP1 MMP3 NOD2 PF4 PPBP XCL1	22 interacting genes: CCL11 CCL13 CCL21 CCL26 CCL28 CCL5 CCL8 CCR3 CXCL11 CXCL12 CXCL14 CXCL17 CXCL6 CXCL9 CXCR3 DPP4 IGFBP7 PF4 PF4V1 PPBP VCAN XCL1
Entrez ID		6357	3627
HPRD ID		03230	00930
Ensembl ID		ENSG00000181374	ENSG00000169245
Uniprot IDs		Q99616	P02778
PDB IDs		2RA4	1LV9 1O7Y 1O7Z 1O80 8K2X
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemotaxis Chemokine Activity Locomotion Chemokine-mediated Signaling Pathway Leukocyte Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Leukocyte Migration Myeloid Leukocyte Migration Humoral Immune Response Immune Response Granulocyte Chemotaxis Cytokine Activity Cell Migration Granulocyte Migration Cytokine-mediated Signaling Pathway Cell Motility Immune System Process Defense Response Inflammatory Response Defense Response To Symbiont Mononuclear Cell Migration Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Killing Of Cells Of Another Organism CCR Chemokine Receptor Binding Cell Killing Response To External Biotic Stimulus Response To Other Organism Positive Regulation Of Leukocyte Migration Regulation Of Leukocyte Migration Eosinophil Chemotaxis Eosinophil Migration Positive Regulation Of Chemotaxis Extracellular Space Response To Stress CXCR Chemokine Receptor Binding Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Extracellular Region Regulation Of Chemotaxis Positive Regulation Of Cell Migration Regulation Of Mononuclear Cell Migration Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Cell Motility Chemokine Receptor Binding Positive Regulation Of Locomotion Cell-cell Signaling Positive Regulation Of Calcium Ion Transport	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Leukocyte Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Leukocyte Migration Cytokine Activity Cell Migration Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Myeloid Leukocyte Migration Humoral Immune Response Granulocyte Migration Cell Motility Killing Of Cells Of Another Organism Inflammatory Response Defense Response Cell Killing CXCR Chemokine Receptor Binding Cytokine-mediated Signaling Pathway Extracellular Space Immune Response Defense Response To Symbiont Immune System Process Defense Response To Other Organism Extracellular Region CCR Chemokine Receptor Binding Response To Other Organism Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Response To External Biotic Stimulus Eosinophil Chemotaxis Eosinophil Migration Neutrophil Chemotaxis Chemokine Receptor Binding Neutrophil Migration Regulation Of Leukocyte Migration Response To Stress Lymphocyte Chemotaxis Regulation Of Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Locomotion Cell-cell Signaling Signaling Signal Transduction
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