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SCNN1B and NFASC
Number of citations of the paper that reports this interaction (PubMedID
11470829
)
32
Data Source:
HPRD
(in vivo)
SCNN1B
NFASC
Description
sodium channel epithelial 1 subunit beta
neurofascin
Image
GO Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Apical Plasma Membrane
Cytoplasmic Vesicle Membrane
Cytoplasmic Vesicle
Sodium Channel Complex
Extracellular Exosome
Plasma Membrane
Focal Adhesion
Membrane
Axon
Paranodal Junction
Node Of Ranvier
Axon Initial Segment
Anchoring Junction
Ficolin-1-rich Granule Membrane
Molecular Function
Sodium Channel Activity
Protein Binding
Ligand-gated Sodium Channel Activity
WW Domain Binding
Protein Binding
Cell-cell Adhesion Mediator Activity
Biological Process
Leukocyte Activation Involved In Inflammatory Response
Neutrophil Activation Involved In Immune Response
Renal System Process
Monoatomic Ion Transport
Sodium Ion Transport
Intracellular Sodium Ion Homeostasis
Regulation Of Blood Pressure
Response To Xenobiotic Stimulus
Gene Expression
Artery Smooth Muscle Contraction
Response To Food
Aldosterone Metabolic Process
Erythrocyte Homeostasis
Monoatomic Ion Transmembrane Transport
Multicellular Organism Growth
Sodium Ion Transmembrane Transport
Epithelial Fluid Transport
Multicellular Organismal-level Water Homeostasis
Sensory Perception Of Salty Taste
Sensory Perception Of Sour Taste
Potassium Ion Homeostasis
Sodium Ion Homeostasis
Mucus Secretion
Neutrophil-mediated Killing Of Bacterium
Cellular Response To Acidic PH
Sodium Ion Import Across Plasma Membrane
Cellular Response To Aldosterone
Cellular Response To Vasopressin
Cell Adhesion
Axon Guidance
Brain Development
Peripheral Nervous System Development
Myelination
Cell-cell Adhesion
Pathways
Stimuli-sensing channels
Sensory perception of salty taste
Interaction between L1 and Ankyrins
Neurofascin interactions
Neurofascin interactions
Neutrophil degranulation
Drugs
Triamterene
Amiloride
Diseases
Liddle syndrome
Bronchiectasis with or without elevated sweat chloride
Hyperkalemic distal renal tubular acidosis (RTA type 4), including the following two diseases: Pseudohypoaldosteronism type I (PHA1); Pseudohypoaldosteronism type II (Gordon's syndrome)
GWAS
Kidney stones (
31729369
)
Age at first sexual intercourse (
34211149
)
Amyotrophic lateral sclerosis (sporadic) (
24529757
)
Blood protein levels (
30072576
)
Clozapine-induced agranulocytosis (
25187353
)
Dental caries (
23064961
)
Diisocyanate-induced asthma (
25918132
)
Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) (
30120083
)
General risk tolerance (MTAG) (
30643258
)
High myopia (
32428537
)
Mean platelet volume (
27863252
32888494
)
Platelet count (
32888494
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
14 interacting genes:
ANK3
CNTN1
COMMD10
EPN1
HECW1
ITCH
NEDD4
NEDD4L
NFASC
SCNN1A
SCNN1D
SCNN1G
STX1A
WWP2
12 interacting genes:
ABI1
ABI2
ANK1
CNTNAP1
DCX
NRCAM
SCN1B
SCN3B
SCNN1B
SDCBP
SDCBP2
TNR
Entrez ID
6338
23114
HPRD ID
02861
12372
Ensembl ID
ENSG00000168447
ENSG00000163531
Uniprot IDs
B2R812
H3BQ95
P51168
A0A7P0Z4R6
B4DRH7
O94856
PDB IDs
6BQN
6WTH
9BLR
9BTG
9BTU
3P3Y
3P40
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Potassium Ion Transmembrane Transport
Sodium Ion Import Across Plasma Membrane
Sensory Perception Of Salty Taste
Negative Regulation Of Potassium Ion Transport
Import Into Cell
Negative Regulation Of Potassium Ion Export Across Plasma Membrane
Cellular Response To Aldosterone
Sodium Channel Complex
Sensory Perception Of Sour Taste
Cellular Response To Vasopressin
Potassium Channel Inhibitor Activity
Transmembrane Transporter Binding
Regulation Of Potassium Ion Export Across Plasma Membrane
Cellular Response To Mineralocorticoid Stimulus
Ligand-gated Sodium Channel Activity
Regulation Of Potassium Ion Transmembrane Transport
Regulation Of Sodium Ion Transport
Sodium Ion Transport
Negative Regulation Of Cation Transmembrane Transport
Response To Aldosterone
Negative Regulation Of Monoatomic Ion Transmembrane Transport
Cellular Response To Acidic PH
Regulation Of Potassium Ion Transport
Intracellular Sodium Ion Homeostasis
Inorganic Cation Import Across Plasma Membrane
Negative Regulation Of Monoatomic Ion Transport
Response To Acidic PH
Ubiquitin-protein Transferase Activity
Cellular Response To PH
Negative Regulation Of Transmembrane Transport
Sensory Perception Of Taste
Sodium Channel Activity
Sodium Ion Homeostasis
Neuromuscular Junction Development
Response To Mineralocorticoid
Sodium Ion Transmembrane Transport
Response To PH
Import Across Plasma Membrane
Regulation Of Metal Ion Transport
Ubiquitin Protein Ligase Activity
Protein Modification By Small Protein Conjugation
Protein Monoubiquitination
Regulation Of Monoatomic Ion Transport
Regulation Of Membrane Potential
Sodium Channel Inhibitor Activity
Regulation Of Dendrite Morphogenesis
Endocytosis
Cellular Response To Corticosteroid Stimulus
Receptor Internalization
Protein K63-linked Ubiquitination
Action Potential Propagation
Neuronal Action Potential Propagation
Cytoskeletal Anchor Activity
Action Potential
System Development
Neuron Migration
Cell Projection Organization
Plasma Membrane Bounded Cell Projection Organization
Sodium Channel Inhibitor Activity
Sodium Channel Complex
Actin-based Cell Projection
Regulation Of Atrial Cardiac Muscle Cell Membrane Depolarization
Nervous System Development
SCAR Complex
Cell Projection Morphogenesis
Voltage-gated Sodium Channel Complex
Membrane Depolarization During Cardiac Muscle Cell Action Potential
SH3 Domain Binding
Filopodium Tip
Neuron Projection
Membrane Depolarization During Action Potential
Sodium Ion Transmembrane Transport
Transmembrane Transporter Binding
Central Nervous System Development
Regulation Of Neuron Projection Development
Regulation Of Membrane Potential
Cell Migration
Nervous System Process
Cell Junction Organization
System Process
Sodium Channel Regulator Activity
Sodium Ion Transport
Positive Regulation Of Sodium Ion Transport
Neuron Projection Development
Sodium Channel Activity
Cardiac Muscle Cell Action Potential Involved In Contraction
Cytoskeleton Organization
Muscle Contraction
Regulation Of Heart Rate By Cardiac Conduction
Cardiac Muscle Cell Action Potential
Cardiac Muscle Contraction
Neuron Projection Guidance
Axon Guidance
Cell Motility
Cardiac Conduction
Neuromuscular Process Controlling Balance
Regulation Of Cellular Component Organization
Regulation Of Membrane Depolarization
Membrane Depolarization
Synapse Organization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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