ATXN1 and RBFOX1

  • Number of citations of the paper that reports this interaction (PubMedID 16713569)
  • 0
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (two hybrid)

ATXN1

RBFOX1

Description ataxin 1 RNA binding fox-1 homolog 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis ( 19451621)
  • Atrial fibrillation ( 30061737 29892015)
  • Breast cancer ( 29059683)
  • Central corneal thickness ( 32528159)
  • Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Cortical amyloid beta load ( 29860282)
  • Fish- and plant-related diet ( 32066663)
  • Gambling ( 22780124)
  • General cognitive ability ( 29844566)
  • Generalized epilepsy ( 30531953)
  • Granulocyte count ( 27863252)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821)
  • HDL cholesterol levels ( 32203549)
  • High light scatter reticulocyte count ( 27863252)
  • High light scatter reticulocyte percentage of red cells ( 27863252)
  • Household income (MTAG) ( 31844048)
  • Immature fraction of reticulocytes ( 32888494)
  • Lymphocyte percentage of white cells ( 32888494)
  • Major depressive disorder ( 23377640)
  • Metabolite levels ( 23823483)
  • Monocyte count ( 32888494)
  • Monocyte percentage of white cells ( 32888494)
  • Multiple sclerosis ( 31604244)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 27863252 32888494 29403010)
  • Neutrophil percentage of white cells ( 32888494)
  • Reticulocyte count ( 27863252)
  • Reticulocyte fraction of red cells ( 27863252)
  • Subcutaneous adipose tissue attenuation (Hounsfield unit scale) ( 27918534)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • Systemic lupus erythematosus ( 27399966 28714469)
  • Total body bone mineral density ( 30172743)
  • Visceral adipose tissue attenuation (Hounslow unit scale) ( 27918534)
  • Waist circumference adjusted for body mass index ( 34021172)
  • White blood cell count ( 29403010 27863252 32888494)
  • 3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134)
  • Adult body size ( 32376654)
  • Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686)
  • Age at first sexual intercourse ( 34211149)
  • Albumin-globulin ratio ( 29403010)
  • Allergic rhinitis ( 25085501)
  • Alzheimer's disease ( 33074286)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Anxiety ( 33859377)
  • Bitter alcoholic beverage consumption ( 31046077)
  • Bitter non-alcoholic beverage consumption ( 31046077)
  • Body mass index ( 28892062 25673413)
  • Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066)
  • Brain volume in infants (cerebrospinal fluid) ( 28763065)
  • Cataracts ( 34127677)
  • Cerebellum white matter volume ( 31530798)
  • Chronotype ( 30696823)
  • Cocaine dependence ( 31212010)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Depression ( 33859377 29700475)
  • Evening vs. morning chronotype (sMEQ score) ( 32579418)
  • Extraversion ( 27918536)
  • Feeling worry ( 29500382)
  • Femur bone mineral density x serum urate levels interaction ( 34046847)
  • General cognitive ability ( 29844566)
  • General risk tolerance (MTAG) ( 30643258)
  • Glaucoma ( 25027321)
  • HDL cholesterol levels in HIV infection ( 33109212)
  • High myopia ( 31816047)
  • Hydrolysed wheat protein allergy ( 31301374)
  • Hyperopia ( 25233373)
  • Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597)
  • Insomnia symptoms (never/rarely vs. usually) ( 30804566)
  • Intelligence (MTAG) ( 29326435)
  • Intracranial aneurysm ( 29531279)
  • joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033)
  • Major depressive disorder ( 29728651 27479909)
  • Mental health study participation (completed survey) ( 31263887)
  • Metabolite levels ( 31628463)
  • Myopia ( 27182965 25233373)
  • Neurociticism ( 29500382)
  • Neurofibrillary tangles ( 31497858)
  • Neuroticism ( 29255261)
  • Nickel levels ( 26025379)
  • Nontraumatic osteonecrosis of the femoral head ( 32701715)
  • Obesity (extreme) ( 31852448)
  • Obesity-related traits ( 23251661)
  • Optic disc size ( 31809533)
  • Photic sneeze reflex ( 27182965)
  • Pit-and-Fissure caries ( 24556642)
  • Refractive astigmatism ( 30306274)
  • Refractive error ( 23396134 32231278 23474815)
  • Renal cell carcinoma ( 31231134)
  • Rheumatoid arthritis ( 30423114)
  • Severe insulin-resistant type 2 diabetes ( 34737425)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Systemising ( 31508503)
  • Systolic blood pressure ( 30224653)
  • Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483)
  • tricyclic pyrone compound response (IC50) ( 33610756)
  • Triglyceride levels ( 34074324)
  • Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926)
  • Type 2 diabetes ( 30130595)
  • Worry too long after an embarrassing experience ( 29500382)
Interacting Genes 289 interacting genes: - ACACA ACOT7 ADAM15 ADCY6 ADD3 AHDC1 AKT1 ANKHD1 ANP32A APBB1 ARHGAP32 ARID5A ASNS ATF5 ATP1A3 ATP6V0D1 ATXN1L ATXN2 ATXN2L BAALC BASP1 BATF2 BEND2 BHLHE40 BICRAL BLTP3B BRD10 BTG3 C10orf55 C1orf94 CAMK1 CAMK2B CCDC136 CCNK CDIP1 CDK6 CDRT15P3 CFL1 CHRNA7 CIC CIRBP CLASRP CLCN2 CLEC4F COIL CPSF7 CREM CRIP2 CRK CRX CRY2 CST3 CUTC DAZ2 DAZAP2 DCTN3 DHRSX DHX37 DIXDC1 DMPK DNAJA3 DOCK5 DZIP3 EFEMP2 EHMT1 EIF1AY EIF1B EIF3F EIF4ENIF1 ELP5 EML3 ENTPD6 EPN2 ESRP1 ESRRA ETV4 EXTL3 FAM153B FAM168A FAM193B FAR1 FAT4 FDPS FHL2 FNDC9 FOSL1 FOXN4 FUBP3 FYN GAPDH GATAD1 GCA GCFC2 GGA2 GMEB2 GPATCH8 GSPT1 H2AP H3C1 HACL2 HEY2 HEYL HIVEP1 HNRNPLL HOTAIR HPCAL1 HSFX1 HSFY1 HSFY2 HSPA1A IGF2R IL34 IMMT IPO8 IST1 ITGB4 KAT5 KAT6A KCNAB2 KCTD15 KIAA1549L KIF22 KLF11 KLHL12 KLHL8 KMT2B KRTAP12-4 KRTAP13-3 LASP1 LDB1 LITAF LOXL1 LPAR2 LRSAM1 MAGEB18 MAGEB2 MAGEB6 MATN2 MBP MED15 METTL17 METTL27 MLST8 MSMO1 MSX2 MTERF4 MYO18A NARS1 NCAM1 NCOR1 NCOR2 NFYA NHSL2 NLGN3 NLK NPHP3 NR4A1 NUDT21 NUMBL NUTM2B OAZ1 OPCML OTX2 PANX2 PEPD PHPT1 PIAS1 PICALM PIM2 PLA2G10 PLEKHB1 PLEKHN1 PML POGZ POM121 POMP PPAT PPP6R2 PQBP1 PRDM1 PRR20A PRR20B PRR20C PRR20D PRR20E PRRC2A PRRC2B PSMC3 PSPH PTGDS PUM1 QKI QRICH1 R3HDM1 R3HDM2 RAD54L2 RAI2 RAPGEF1 RAPGEF4 RBFOX1 RBFOX2 RBM26 RBPMS RCC1L RCN1 REL RHOXF2 RNF10 RNF31 RNF4 SAR1A SEMA4G SETD2 SETD6 SF1 SGMS1 SIX5 SLC25A51 SLC4A2 SLC51A SLC6A13 SMARCC2 SORCS3 SOX3 SPEN SREBF1 SREBF2 ST6GALNAC6 STAC2 STAM2 SUGP2 SUMO1 SUPT20H SV2A SYBU TBC1D5 TBX15 TCAP TCEANC TCTA TDP2 TENT5A TENT5B TMX2 TOLLIP TOMM20 TOX4 TP53I11 TPRX1 TRAF2 TRIM32 TRIM38 TRIP6 TSC1 TTC19 U2AF2 UBAP2L UBE2E3 UBE2I UBQLN4 UHRF2 UNK USP54 USP7 VCP VSNL1 VSTM2L WASHC2C WNK1 WNK2 YWHAE YWHAZ YY1AP1 ZBTB32 ZC3H10 ZC3H7B ZCCHC13 ZHX1 ZHX2 ZHX3 ZNF276 ZNF488 ZNF609 ZNF804A ZSCAN1 ZSWIM8 ZXDC ZYX 49 interacting genes: AGR2 ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN SPMIP9 STRBP TNIP1 TOLLIP UBL3 VENTX
Entrez ID 6310 54715
HPRD ID 03333 16091
Ensembl ID ENSG00000124788 ENSG00000078328
Uniprot IDs A0A2R8YCF3 P54253 Q96FF1 A0A6Q8PH77 A0A804HJM2 A0A804HKG7 B7Z1U7 F8VZG9 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44
PDB IDs 1OA8 2M41 4APT 4AQP 4J2J 4J2L 6QIU 2ERR 2N82 4ZKA 7VRL
Enriched GO Terms of Interacting Partners?
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