RBFOX1 and ALG13

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		RBFOX1	ALG13
Gene Name		RNA binding protein, fox-1 homolog (C. elegans) 1	ALG13, UDP-N-acetylglucosaminyltransferase subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network	Endoplasmic Reticulum Membrane
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase Activity Cysteine-type Peptidase Activity Carbohydrate Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of RNA Splicing RNA Transport Neuromuscular Process Controlling Balance	Dolichol-linked Oligosaccharide Biosynthetic Process Proteolysis Protein N-linked Glycosylation Via Asparagine Lipid Glycosylation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways			Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Defective ALG11 causes ALG11-CDG (CDG-1p) Diseases associated with N-glycosylation of proteins
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Refractive error ( 23396134 23474815)
Protein-Protein Interactions		33 interactors: ALG13 ATN1 ATXN1 ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 KIFAP3 LZTS2 MAGED1 NOC2L NUMBL PCBP4 PRR20A PRRC2A PSMF1 QKI RBFOX2 RBM24 RBPMS RHOXF2 SNRPN TNIP1	7 interactors: ATN1 ATXN1L HOXA1 MAPKBP1 PITX1 RBFOX1 RERE
Entrez ID		54715	79868
HPRD ID		16091	06542
Ensembl ID		ENSG00000078328	ENSG00000101901
Uniprot IDs		B7Z1U7 F5H0M1 Q59HD3 Q9NWB1	Q9NP73
PDB IDs		2ERR
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Cellular Process RNA Splicing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of RNA Splicing Cellular Macromolecule Biosynthetic Process Negative Regulation Of Signaling Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cell Migration In Hindbrain Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Canonical Wnt Signaling Pathway Hindbrain Development Biosynthetic Process Circadian Rhythm Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression MRNA Processing Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Calcium-dependent Cell-cell Adhesion Positive Regulation Of Photoreceptor Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cerebellum Morphogenesis Regulation Of MRNA Stability Hindbrain Morphogenesis Regulation Of RNA Stability Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Metabolic Process	RNA Metabolic Process Gene Expression Regulation Of RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Optokinetic Behavior Abducens Nerve Formation Cellular Macromolecule Biosynthetic Process Neuromuscular Process Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Facial Nucleus Development Positive Regulation Of Hematopoietic Stem Cell Proliferation Branchiomeric Skeletal Muscle Development Semicircular Canal Formation Rhombomere 4 Development Rhombomere 3 Development Rhombomere 5 Development Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Central Nervous System Development Myoblast Fate Commitment Multicellular Organismal Development Regulation Of Hematopoietic Stem Cell Proliferation Biosynthetic Process Embryonic Neurocranium Morphogenesis Outer Ear Morphogenesis Semicircular Canal Morphogenesis Rhombomere Development Maintenance Of Cell Polarity Facial Nerve Structural Organization Pons Development Facial Nerve Morphogenesis Developmental Process Toxin Metabolic Process Semicircular Canal Development Parasympathetic Nervous System Development NLS-bearing Protein Import Into Nucleus Anatomical Structure Arrangement Cellular Metabolic Process Cochlea Morphogenesis
Tagcloud ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	34a abcf2 adhesions bioinformatics chance ctcf fak held kaplan ki67 lyar meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr
Tagcloud (Difference) ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	34a abcf2 adhesions bioinformatics chance ctcf fak held kaplan ki67 lyar meier michigan mir nbl neuroblastoma originates proteome proteomics searches seed sh shep sy5y sympathetic tetracycline tgm2 timm13 utr
Tagcloud (Intersection) ?