RBFOX1 and RBFOX2

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		RBFOX1	RBFOX2
Gene Name		RNA binding protein, fox-1 homolog (C. elegans) 1	RNA binding protein, fox-1 homolog (C. elegans) 2
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Trans-Golgi Network	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding	Nucleotide Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding Transcription Factor Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing Regulation Of RNA Splicing RNA Transport Neuromuscular Process Controlling Balance	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Regulation Of Definitive Erythrocyte Differentiation RNA Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Intracellular Estrogen Receptor Signaling Pathway Regulation Of Cell Proliferation Negative Regulation Of Transcription, DNA-templated Dendrite Morphogenesis Neuromuscular Process Controlling Balance
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Refractive error ( 23396134 23474815)
Protein-Protein Interactions		33 interactors: ALG13 ATN1 ATXN1 ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 KIFAP3 LZTS2 MAGED1 NOC2L NUMBL PCBP4 PRR20A PRRC2A PSMF1 QKI RBFOX2 RBM24 RBPMS RHOXF2 SNRPN TNIP1	50 interactors: APH1A ATN1 ATXN1 ATXN1L BOLL BRD7 C1orf94 CAMK2B CHAF1A DAB1 DAZAP2 DDX5 DEDD2 DMRTB1 ELAVL1 ELAVL2 ESR1 ESR2 GLIS2 GTF2A1L HNRNPAB HNRNPF HNRNPH2 HNRNPK KHDRBS1 MAGED1 MAPK1IP1L MED7 NAF1 NR2E3 POLR3D PSMA3 PSMF1 PTBP1 QKI RBFOX1 RBM22 RBM23 RBM42 RBPMS RERE RHOXF2 RNF8 SF3A1 SMN1 SNRPC TOLLIP U2AF2 VAC14 ZNF137P
Entrez ID		54715	23543
HPRD ID		16091	15231
Ensembl ID		ENSG00000078328	ENSG00000100320
Uniprot IDs		B7Z1U7 F5H0M1 Q59HD3 Q9NWB1	O43251
PDB IDs		2ERR	2CQ3
Enriched GO Terms of Interacting Partners?		Gene Expression RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Cellular Process RNA Splicing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Negative Regulation Of Signal Transduction RNA Biosynthetic Process Regulation Of RNA Splicing Cellular Macromolecule Biosynthetic Process Negative Regulation Of Signaling Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Cell Migration In Hindbrain Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Canonical Wnt Signaling Pathway Hindbrain Development Biosynthetic Process Circadian Rhythm Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression MRNA Processing Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Positive Regulation Of Calcium-dependent Cell-cell Adhesion Positive Regulation Of Photoreceptor Cell Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cerebellum Morphogenesis Regulation Of MRNA Stability Hindbrain Morphogenesis Regulation Of RNA Stability Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Metabolic Process	Gene Expression RNA Metabolic Process RNA Processing Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Processing Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of MRNA Processing Positive Regulation Of Cellular Protein Metabolic Process Metabolic Process DNA-templated Transcription, Initiation
Tagcloud ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Difference) ?		16p13 2p13 3p13 abat anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 spanning tmem114 vertebral	aberrant altering biology discussing editing emerging fmrp focus fus hub huc hud hur neurological nova players polyadenylation processing qki rbp rbps rna rnas roles splicing steps surveillance translational
Tagcloud (Intersection) ?