MARCHF6 and BUD31

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		MARCHF6	BUD31
Description		membrane associated ring-CH-type finger 6	BUD31 spliceosome associated protein
Image		No pdb structure
GO Annotations	Cellular Component	ER Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Quality Control Compartment	Chromatin Nucleus Nucleoplasm Spliceosomal Complex Centrosome Microtubule Cytoskeleton U2-type Catalytic Step 2 Spliceosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Enzyme Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding	Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding
	Biological Process	Cholesterol Biosynthetic Process Proteasomal Protein Catabolic Process Protein Ubiquitination ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Protein K48-linked Ubiquitination Endoplasmic Reticulum Mannose Trimming	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Positive Regulation Of DNA-templated Transcription
Pathways		ER Quality Control Compartment (ERQC)	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Facial emotion recognition (sad faces) ( 28608620) Serum metabolite levels ( 23093944)
Interacting Genes		12 interacting genes: ADGRE2 BUD31 DIO2 MSMO1 MTNR1B RGS2 SQLE UBC UBE2D2 UBE2G1 UBE2G2 UBE2J2	25 interacting genes: ADCY7 APP ATP13A1 BEND5 CCT3 CEBPA CTNNBL1 ERGIC3 HLA-A HOXA1 HTR5A KRTAP10-3 KRTAP10-7 MARCHF6 MEOX2 MMP24 NPC1 PANX1 PICK1 RELB RNF208 SCAF1 SF1 TMEM94 TSPAN7
Entrez ID		10299	8896
HPRD ID		11095	10351
Ensembl ID		ENSG00000145495	ENSG00000106245
Uniprot IDs		O60337	P41223
PDB IDs			4OED 4OH6 4OKB 5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7AAV 7ABF 7ABG 7ABI 7QTT 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8Q7N 8QO9 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Ubiquitin Protein Ligase Binding Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Cholesterol Biosynthetic Process Post-translational Protein Modification ATP Binding Sterol Biosynthetic Process Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Squalene Monooxygenase Activity Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Membrane Macromolecule Catabolic Process Ubiquitin-protein Transferase Activity Nucleotide Binding Negative Regulation Of Glycine Import Across Plasma Membrane Proteolysis Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity Thyroid Hormone Catabolic Process Steroid Biosynthetic Process C-4 Methylsterol Oxidase Activity Response To Biphenyl Catabolic Process ERAD Pathway Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Adenylate Cyclase Inhibitor Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?