MARCH6

Gene Name		membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity Enzyme Binding Ubiquitin Conjugating Enzyme Binding
	Biological Process	Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Body mass index ( 22446040)
Protein-protein Interactions		3 interactors: DIO2 UBE2D2 UBE2G1
Entrez ID		10299
HPRD ID		11095
Ensembl ID		ENSG00000145495
Uniprot IDs		O60337
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Thyroid Hormone Catabolic Process Catabolic Process Selenocysteine Incorporation Hormone Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Thyroid Hormone Generation Cellular Modified Amino Acid Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Thyroid Hormone Metabolic Process Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Cellular Protein Metabolic Process Hormone Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Proteolysis Phenol-containing Compound Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Metabolic Process Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response
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