SALL2 and CUL4A

Number of citations of the paper that reports this interaction (PMID 21228219)
4

Data Source:
BioGRID (pull down)

		SALL2	CUL4A
Gene Name		spalt-like transcription factor 2	cullin 4A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	NuRD Complex	Cul4A-RING E3 Ubiquitin Ligase Complex Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Transcription, DNA-templated Neural Tube Development	G1/S Transition Of Mitotic Cell Cycle DNA Repair Cell Cycle Arrest Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Viral Process Protein Ubiquitination Hemopoiesis Negative Regulation Of Granulocyte Differentiation Somatic Stem Cell Maintenance Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Intrinsic Apoptotic Signaling Pathway Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint Regulation Of Nucleotide-excision Repair
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ADAMTSL4 CEP76 CUL4A CUL4B DDB1 EWSR1 RBBP7 ZMIZ2	21 interactors: CAND1 CDKN1B CHEK1 COMMD1 COPS2 COPS5 DCUN1D1 DCUN1D3 DCUN1D4 DCUN1D5 DDB1 DDB2 HIST1H1C HIST1H3A HOXA9 RBX1 RNF7 SALL2 SENP8 SKP2 UBE2E3
Entrez ID		6297	8451
HPRD ID		03743	07218
Ensembl ID		ENSG00000165821	ENSG00000139842
Uniprot IDs		E7EW59 Q9Y467	B2RBV7 Q13619
PDB IDs			2HYE 4A0K
Enriched GO Terms of Interacting Partners?		UV-damage Excision Repair Histone H2A Monoubiquitination Histone H2A Ubiquitination Regulation Of Cell Cycle Process Histone Monoubiquitination Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Histone Ubiquitination Protein Monoubiquitination Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Cellular Response To UV DNA Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Nucleotide-excision Repair Cellular Response To Light Stimulus Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Heat Acclimation Positive Regulation Of Mitotic Cell Cycle Cellular Protein Catabolic Process Protein Ubiquitination DNA Repair Chromatin Modification Protein Modification By Small Protein Conjugation Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Catabolic Process Response To UV Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Stress Cellular Response To Radiation Proteolysis Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Organization Cellular Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Positive Regulation Of Cell Cycle Process Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Granulocyte Differentiation Nitrogen Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process See more	Protein Deneddylation Protein Ubiquitination Protein Modification By Small Protein Conjugation Response To UV Protein Monoubiquitination UV-damage Excision Repair Cellular Response To UV Cullin Deneddylation Cellular Protein Modification Process Protein Neddylation Histone H2A Monoubiquitination Cellular Response To Light Stimulus Histone H2A Ubiquitination Nucleotide-excision Repair, DNA Damage Removal Histone Monoubiquitination Protein Modification By Small Protein Removal Response To Light Stimulus Cellular Response To Radiation Response To Abiotic Stimulus Chromatin Organization Cellular Protein Metabolic Process Protein Polyubiquitination Histone Ubiquitination Response To Radiation Cellular Response To DNA Damage Stimulus Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Phase Transition Proteasomal Protein Catabolic Process Cell Cycle Phase Transition Cellular Response To Stress Chromosome Organization DNA Repair Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription DNA Metabolic Process Cellular Response To Cell-matrix Adhesion Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage SCF Complex Assembly Histone H3-T11 Phosphorylation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Nucleotide-excision Repair Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly See more
Tagcloud ?		adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1	aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott
Tagcloud (Difference) ?		adding ap4 bioinformatic deregulated deregulation doxorubicin electrophoretic embryo evidences genotoxic half hydroxy knockin mefs necessarily neurotrophin p53er r175h r248w r249s radiosensitive repress repressed represses spalt tam tamoxifen unable wt1	aldrich ambra1 arp2 associates autophagy becn1 ddb1 e3 elusive endosomal impairs impede interactor k48 k63 ligase linkage pik3c3 potentiates rnf2 scar sorting starvation suppresses ubiquitinate ubiquitination wash wasp wiskott
Tagcloud (Intersection) ?